Where Can I Get Cell Treatment for Knee Pain?

Around 790,000 Americans undergo total knee replacement surgery annually, often after years of battling pain and reduced mobility. Some turn to addictive medications only to find temporary relief. While knee surgery may seem like the final answer, what if there was a minimally invasive alternative?

cell therapy is a promising alternative, tapping into your body’s natural healing abilities without the long recovery times or dependency on medication. In this article, we’ll cover the most popular destinations and the top 10 clinics specializing in stem cell knee injections.

Table of Contents

1. Best Countries Offering Cell Injections for Knees
2. Top 10 Clinics for Knee Cell Therapy Worldwide
3. Next Steps
4. FAQ

Best Countries Offering Cell Injections for Knees

If you’re considering knee stem cell therapy, some of the best options lie beyond U.S. borders. In the U.S., this treatment is still under review by the FDA. It hasn't yet been widely approved for use outside of clinical trials. This makes it harder to find reliable and affordable treatment options domestically. 

Other countries’ regulatory bodies, like Colombia’s INVIMA, have approved stem cell therapies, allowing for verified, accessible treatment options. Fewer regulatory hurdles in these countries lead to lower treatment costs. This also gives medical professionals more freedom to innovate and explore new advancements in regenerative therapy.

🤔 Where can I get stem cell treatment for knee problems?

The regions that stand out for their stem cell therapy options are:

✈️ Latin America (Mexico, Colombia). The proximity to the U.S. means shorter travel, while competitive pricing and the latest technologies make these countries a prime spot for medical tourists and celebrities alike.

✈️ Middle East (Turkey, Israel). Turkey has rapidly become a hub for medical tourism, offering knee stem cell treatment with advanced techniques. Israeli clinics, known for their stem cell research, provide progressive care backed by years of innovation in regenerative medicine.

✈️ Europe (Switzerland). Switzerland is known for its premium healthcare system and high-end stem cell therapies. While the costs here are higher, the quality and precision of treatment make Switzerland a top choice for those seeking elite medical care.

✈️ Asia (Thailand). Thailand has built a reputation as a leader in medical tourism, providing exceptional care at significantly lower costs compared to other regions.

Bookimed has analyzed data from over 150 partner clinics offering knee stem cell injections, along with insights from the broader market. Here’s how the costs in these regions stack up against U.S. prices:

Country	Cost
United States	$5,000 - $12,000 (per knee)
Mexico	$2,000 - $4,000
Colombia	$5,000 - $9,000
Turkey	$3,000 - $5,500
Israel	$4,000 - $6,000
Switzerland	$5,000 - $11,000
Thailand	$5,000 - $6,000

❗ Note that the U.S. prices are for one knee only, while medical tourism hubs often include both knees and extra perks like consultations, post-care, transfers, and accommodation in their packages.

On average, knee stem cell therapy in these regions is 2 to 4 times more affordable than in the U.S. This substantial difference comes down to fewer regulatory barriers, lower operational costs, and a highly competitive medical tourism industry.

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Top 10 Clinics for Knee Cell Therapy Worldwide

Using our Ranking Policy, we evaluated our partner clinics based on: 

• patient demand;
• reviews;
• available treatment programs;
• quality of communication;
• achievements, certifications, and awards. 

As a result, we’ve selected the top 10 clinics across key regions for high-quality knee stem cell treatment.

Clinic	Location	Description	Approximate Costs
Cellular Hope Institute	Cancun, Mexico	A regenerative medicine center with 12 years of expertise in immunology and rheumatology. Offers 4-star hotel accommodation and VIP transfers.	$7,000 per 1 stem cell knee injection
Liv Hospital Ulus	Istanbul, Turkey	Uses patients' own for orthopedic treatments. Certified by the Turkish Ministry of Health for stem cell therapies.	Upon request
ID Clinic Bangkok	Bangkok, Thailand	Uses mesenchymal from umbilical cord donors. cells undergo a rigorous screening process to ensure safety.	From $5,500
Medical Center Juventa	Playa del Carmen, Mexico	A leader in regenerative medicine with its own stem cell bank and laboratory. Offers personalized home care and boasts an 80% success rate.	$1,600 - $4,800
Medipol Mega University Hospital	Istanbul, Turkey	One of Turkey’s leading hospitals, specializing in stem cell treatments for joint diseases like arthrosis. JCI-accredited, handles over 1 million patients annually.	$4,000 - $7,500
Immunotherapy Regenerative Medicine	Puerto Vallarta, Mexico	Uses for chronic knee pain and sports injuries. Features a team of biologists and medical experts with 20 years of experience.	$4,000 - $6,200
Giostar	Cancun, Mexico	A global leader in stem cell research and therapy, headquartered in San Diego, USA. Treatment cost includes nutritional IV therapy and dietary guidance during recovery.	$8,500
Reju Medical Clinic	Medellín, Colombia	Focuses on arthritis, chronic knee pain, and autoimmune diseases. The team has over 15 years of experience.	Depends on condition
Sourasky Medical Center	Tel Aviv, Israel	Israel’s largest multidisciplinary medical center, ranked among the top 10 clinics for medical tourists worldwide. Offers Orthokine therapy to promote healing.	$6,500
LaCLINIQUE of Switzerland®	Lugano, Switzerland	Led by Adolfo Panfili, President of the International Association of Orthomolecular Medicine. Offices in Switzerland, Italy, and Dubai.	$7,800–$11,000

🏨 Cellular Hope Institute — Cancun, Mexico (from $7,000)

Located in the heart of Cancun’s " Cell Circle," Cellular Hope Institute boasts 12 years of experience. Their comprehensive protocols combine exosomes, allogeneic mesenchymal cells, and autologous cells to alleviate chronic knee pain. 

🤩 Wow-Factor: Cellular Hope Institute treats high-profile patients, including athletes like Mike Tyson and Cristiano Ronaldo.

🏥 Accreditation and Expertise: The clinic is accredited by the Mexican General Health Council and COFEPRIS (the Mexican FDA equivalent). It features a team of top specialists—from radiologists to regenerative medicine experts.

🔬 Facilities: The clinic boasts a state-of-the-art laboratory for cell culture expansion, resulting in improved patient outcomes. Additionally, a cryopreservation unit keeps stem cell samples safely stored for future treatments.

🏨 Liv Hospital Ulus — Istanbul, Turkey

Liv Hospital spans 30,000 m² with 50 specialized clinics, including Centers of Excellence certified by Surgical Review Corporation. Every year, around 50,000 international patients choose Liv for advanced treatments.

🧫 Expertise: Liv orthopedists utilize for tissue regeneration at the Cell Research & Manufacturing Center. This treatment is available for individuals aged 15-55 with cartilage and tendon injuries, joint degeneration, or sports-related traumas.

🤩 Wow-Factor: The clinic uses at least 3 million per 1 cm of the lesion, ensuring thorough treatment.

🏨 ID Clinic — Bangkok, Thailand (from $5,500)

ID Clinic specializes in mesenchymal stem cell (MSC) treatments for conditions like autoimmune diseases and knee joint pain. The clinic’s packages cover all necessary expenses, such as pre-op check-ups, lab tests, doctor fees, anesthesia, and post-procedure care.

🤩 Wow-Factor: The clinic uses mesenchyme cells derived from umbilical cord blood, renowned for their ability to self-renew and repair damaged tissue. Its specialists carefully test to ensure purity and safety. 

🏨 Medical Center Juventa — Playa del Carmen, Mexico (from $1,600)

Medical Center Juventa focuses on orthopedics, endocrinology, and immunology. The clinic specializes in treating knee joints, knee osteoarthritis, and rheumatoid arthritis. The cost of treatments includes private transfers and accommodation.

🧫 Expertise: Dr. Isabella Bernaschina, a specialist with over a decade of experience, conducts stem cell treatments at the center. She is a certified member of RCG, the leading medical community of regenerative medicine in Mexico.

🏨 Medipol Mega University Hospital — Istanbul, Turkey (from $4,000)

Medipol Mega University Hospital is one of Turkey's largest multi-specialty medical centers. Its team treats over 1,200 patients daily. Medipol’s Orthopedics and Traumatology Department uses for knee diseases and injuries.

🧫 Expertise: The hospital’s orthopedists are among the few in Turkey qualified to perform stem cell knee injections. They offer specialized therapies for patients with knee joint pathologies or trauma.

🏨 Immunotherapy Regenerative Medicine — Puerto Vallarta, Mexico (from $4,000)

For over 20 years, Immunotherapy Regenerative Medicine Center has been a leader in this field. The clinic boasts a multidisciplinary team of biologists, biophysicists, biochemists, and nutritionists. The clinic is fully licensed and regulated by COFEPRIS, guaranteeing the highest safety and quality standards.

🧫 Expertise: The clinic offers knee treatments with a unique blend of 100 million fresh mesenchymal , 1 billion exosomes, and () enhanced with ozone. What sets the clinic apart is the ability to customize therapy based on the patient’s unique needs, using sourced from dental tissue, placenta, Wharton’s jelly, and endometrial tissues.

🤩 Wow-Factor: Immunotherapy Regenerative Medicine stands out by using only fresh cells, avoiding freezing during transport to keep the cells fully active. This ensures a higher success rate for treatments.

🏨 Giostar — Mexico (from $8,500)

Giostar Cell Therapy Clinic has three locations in Mexico—Los Algodones, Playa del Carmen, and Guadalajara—all certified by COFEPRIS. Giostar specializes in treating a broad range of conditions, including joint and muscular diseases, autoimmune diseases, and sports injuries. As pioneers in stem cell technology, GIOSTAR’s team of scientists and clinicians has been at the forefront of stem cell research for over 20 years.

🤩 Wow-Factor: GIOSTAR’s headquarters in San Diego, California, directly links the clinic to the latest in U.S. stem cell research and medical innovation.

🏨 Reju Medical Clinic — Medellín, Colombia

Reju Medical Clinic is a global regenerative medicine provider with additional branches in Mexico, Belgium, Thailand, and Azerbaijan. The clinic specializes in treating autoimmune diseases, musculoskeletal injuries, and other medical conditions that are difficult to manage with traditional treatments. All procedures are conducted by highly experienced professionals, each with 15+ years in the field of stem cell therapies.

🧫 Expertise: Reju offers a minimum of 3 stem cell applications throughout the treatment. They use umbilical cord blood collected from healthy women after C-section births. These donations are thoroughly screened for diseases to ensure safety.

🏨 Sourasky (Ichilov) Medical Center — Tel Aviv, Israel (from $6,400)

As Israel's largest multidisciplinary medical facility, Sourasky Medical Center treats over 400,000 patients annually. Newsweek ranks it among the top 10 clinics for medical tourists worldwide.

🤩 Wow-Factor: Sourasky offers Orthokine therapy, a revolutionary and natural way to treat knee osteoarthritis, knee pain, and tendon or muscle injuries. This therapy uses the patient’s own blood to produce an anti-inflammatory protein. It is then injected into the affected area, offering drug-free relief.

🏨 LaCLINIQUE — Switzerland (from $8,000)

Last but certainly not least on our list, LaCLINIQUE of Switzerland® is a prominent healthcare provider with locations across Switzerland, Italy, and Dubai. LaCLINIQUE leverages international collaborations with Brazil, Mexico, the U.S., Italy, and other countries to stay on the cutting edge of stem cell therapies.

🤩 Wow-Factor: Patients receive under the care of Prof. Adolfo Panfili, the President of the International Association of Orthomolecular Medicine (AIMO). Prof. Panfili is an orthopedic surgeon and a student of Linus Pauling, the Nobel Prize-winning inventor of orthomolecular medicine. He pioneered techniques blending regenerative medicine with orthomolecular sciences to repair cartilage, bone, and joint structures.

🧫 Expertise: LaCLINIQUE offers injections of sourced from the patient’s adipose tissue (ADSCs). This technique is ideal for mild to moderate orthopedic issues affecting the knee, hip, shoulder, ankle, and other joints.

Next Steps

If you’re still unsure where to head for treatment, Bookimed is here to help. Here’s how to get started:

💚 Submit a request on the Bookimed website.
💚 Explore personalized suggestions from your medical coordinator, tailored to your needs and budget.
💚 Receive a treatment plan designed just for you.
💚 Schedule your treatment and arrange your trip with full support from Bookimed.
💚 Enjoy Bookimed’s 24/7 assistance, free of charge, from choosing a clinic to returning home.

Let Bookimed make your experience smooth and stress-free!

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FAQ

Why are so powerful?

cells can transform into different types of cells and amplify the body’s natural repair system. They promote the healing process by self-renewing and replacing cells affected by knee injury or disease. cells are used for conditions like joint pain, autoimmune diseases, and degenerative disorders to support tissue repair and recovery.

How do work for knee pain?

Injected target the root cause of knee pain by repairing damaged tissue. cells also release anti-inflammatory molecules, which reduce swelling and chronic pain while creating a better healing environment.

What are the knee conditions treated with stem cell therapy?

cell injections are effective for various knee issues, including:

• osteoarthritis;
• rheumatoid arthritis; 
• meniscus tears;
• ligament injuries;
• tendon tears;
• cartilage damage.

How do doctors administer stem cell therapy?

For maximum benefit, are processed and concentrated after extraction. Doctors then inject the concentrated stem cell sample directly into the knee joint. This medical procedure is quick and virtually painless.

How effective are for knees?

Research shows that 79.3% of patients experience pain relief and improved function after a stem cell knee injection. This therapy is particularly effective in early to moderate stages of knee degeneration, with clinical studies showing positive outcomes even after a single injection. 

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Where do doctors get for knees?

Doctors can retrieve from the patient’s body (autologous) or from donor tissue through a stem cell bank (allogeneic).

The most popular types of mesenchymal used for knee treatments are:

• Bone m (BMSCs) are adult harvested from , the soft, spongy tissue inside bones.
• Adipose-derived (ASCs) are adult derived from the fat tissue. 
• Umbilical cord (UC-MSCs) are pluripotent collected from donated umbilical cords.

Is stem cell therapy safe?

cell therapy is a safe treatment, with only minor risks like temporary swelling or discomfort at the injection site. Proper sterilization and the use of regulated clinics, such as those available through Bookimed, ensure the safety of the stem cell procedure.

Does insurance cover stem cell therapy?

Unfortunately, stem cell therapy for knees is usually not covered by insurance, as it is still considered experimental and has yet to be approved by the FDA. However, coverage may expand as more research confirms its effectiveness.

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