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Professor Carlo Selmi is leading the Rheumatology and Clinical Immunology Unit at Humanitas Research Hospital.  Since 2009, he is the responsible of the Autoimmunity and Metabolic Laboratory, dedicated to the study of the possible mechanism linked to the progression of autoimmune diseases.  The research focuses on four main areas:  - The epigenetic mechanisms that regulate the environment-genomic interface by influencing the susceptibility and the phenotype of chronic autoimmune and inflammatory diseases in the model of discordant monozygotic twins for disease. To date, the laboratory has biological sample of discordant couples for numerous diseases. - The target antigens of autoimmunity modifications that affect the development of the course of autoimmune diseases. In particular, the laboratory studies the post-translational modifications of joint collagen in rheumatoid arthritis. - The prevalence of non-organ autoantibodies, such as anti-nucleus and anti-ENAs and disease specific autoantibodies, such as anti-citrulline and anti-endomysium in a non-specific population of health adults and the significance of the positive founds over time. - Gender medicine in real-life, through the analysis of administrative databases. The team holds dedicated clinics also for, spondiloarthritis and connetcive tissue disease, and it is active in articular ultrasound, videocapillaroscopy, arthrocenthesis and joint injection of steroid or hyaluronic acid.  The Division includes an inpatient clinic for complex cases. All group members are fluent in spoken and written English Current Teaching Activity: Professor Selmi works as Assistant Professor of Rheumatology at the University of Milan since 2006. Furthermore, he holds a joint appointment as Assistant Professor of Medicine at the Division of Rheumatology of the University of California at Davis since 2005. He is member of the American College of Rheumatology, American Association of Allergists and Immunologists, and the Italian Society of Rheumatology. He serves on the International Group for Research on Psoriatic Disease (GRAPPA) and the working group for autoantibody standardization within the ACR (ASC).   Publications: Selmi C[Author] - Search Results - PubMed (nih.gov)