Knee replacement in Italy: Our Best Clinics and Costs 2025

➜ Best hospital for knee replacement in Italy

Doctors of the clinic are the 1st in Italy that have performed the total knee replacement (arthroplasty).

➜ Over 800 knee replacement arthroplasties are carried out here annually.

➜ Knee replacement with small implants

During this procedure specialists remove only the damaged part of the cartilage. Doctors of the Institute are among the 1st designers of endoprosthesis for the knee in Europe.

The Ospedale San Carlo di Nancy, a first-aid facility accredited by the Italian National Health Service, was acquired by GVM Care & Research in May 2015 and underwent a restructuring and reorganization process.

Founded in 1932, the San Carlo of Nancy Hospital is located on the Via Aurelia, not far from the Vatican City. The facility, classified as a general local hospital since September 1976, can treat about 15,000 patients a year under ordinary hospitalization. To date, the facility has about 450 professionals, including the medical and paramedical staff.

Ospedale San Raffaele (San Raffaele Research Hospital) in Milan is one of the largest research hospitals in Europe. It applies ad hoc methods for rare immune system and genetic diseases treatment.

Among its achievements — the world's first stem cell therapy for patients with severe combined immune deficiency disorder (ADA-SCID).

Oncology, oncohematology, neurosurgery, neurology, cardiovascular surgery, urology, and gynecology are the strongest specialities here.

Surgeons of the hospital perform over 52,000 operations annually.

Founded in 1973 as the first hospital of GVM Care Research, Maria Cecilia Hospital is internationally renowned for advanced treatments in heart surgery, electrophysiology, neurosurgery, and diabetic foot care. Its research has been featured in prestigious medical journals and is recognized as one of Italy’s top medical centers. The hospital handles over 15% of cardiac surgeries in Italy, with complex cases managed by a multidisciplinary Heart Team, including cardiologists, cardiac surgeons, and anesthesiologists.

Additionally, it houses the GVM Campus, which hosts international medical congresses and training events. The hospital is conveniently located 40 minutes from Bologna International Airport and offers transfer services for patients.

Located in Oblia (Sardinia), Mater Olbia Hospital is an international center of excellence, created by combining the skills and the respective experiences of Qatar Foundation Endowment and Fondazione Policlinico Universitario Agostino Gemelli IRCCS in Rome.

The Mater Olbia Hospital is a preferred destination for patients from around the world, in search of top-level expertise, cutting-edge technology and modern and luxurious premises.

Orthopedic in Rome is a medical center in Italy specializing in hip and knee prosthetic surgery. It provides services for both international and local patients seeking quality care. The experienced orthopedic surgeons and dedicated staff offer personalized treatment plans that prioritize comfort and recovery. The clinic's state-of-the-art facilities and advanced surgical techniques ensure the highest standards of care from initial consultation to post-operative rehabilitation.

Founded in 1969, Ospedale Santa Maria in Bari is accredited by the Italian Health Service with numerous first-class medical services. Born as a maternity clinic in the 1960s, the hospital still stands out today as the center of in treatment, prevention, diagnosis, and treatment of women's health. The hospital is home to the Breast Unit, a multidisciplinary unit dedicated to the prevention and treatment of breast cancer, which treats around 500 patients every year.