Best Stem Cell Therapy Clinics and Costs in 2025

What are ?

are unique cells that can develop into many different cell types in the human body. They serve as the body's internal repair sy that divides and replenishes other cells as needed. Unlike other cells with specific functions, can transform into specialized cells like muscle, nerve, or blood cells.

This flexibility makes them vital in regenerative medicine, where they are used to repair or replace damaged tissues and organs.

What is regenerative medicine?

Regenerative medicine focuses on repairing, replacing, or regenerating damaged tissues and organs to restore normal function. Unlike traditional treatments that often focus on managing symptoms, regenerative medicine aims to heal the underlying cause of the problem.

Regenerative medicine centers use advanced techniques like therapy, tissue engineering, and therapy to encourage the body to heal itself. For example, can regenerate damaged heart tissue or repair spinal cord injuries.

📺 Learn how are changing the future of healthcare by watching our exclusive interview with Dr. Isabella Bernaschina.

What types of are used in regenerative medicine?

come from three primary sources: embryos, adult tissues, reprogrammed adult somatic cells, and umbilical tissues.

1. Embryonic . These cells come from early-stage embryos and can develop into almost any type of cell in the body. Their versatility makes them valuable for a wide range of treatments and research.

2. Adult . Found in tissues like and fat, these cells are more specialized and can only become certain types of cells. 

3. Induced pluripotent (iPSCs). These are adult cells reprogrammed to behave like embryonic , so they can develop into many different cell types. iPSCs are useful for personalized treatments since scientists can create them from a patient’s own cells.

4. Perinatal . These cells from the tissues of the umbilical cord, placenta, and amniotic fluid. They share some properties with both embryonic and adult , offering a unique potential for regenerative treatments.

can also be categorized according to the person they come from:

• . These are collected from the patient (often from or fat tissue), processed, and then reintroduced into the same patient. Since the cells are the patient’s own, the risk of rejection or complications is minimal. 
• . banks collect and store from various donors. They can come from umbilical cord blood collected at birth, placental tissue, or adult donors. The cells are thoroughly screened and tested for compatibility and disease to ensure they are safe and effective for use in therapies.

What can treat?

Due to ' unique abilities, they span the full spectrum of potential applications. Scientists are still exploring promising treatments.

Simple injections for orthopedic conditions tend to be more affordable, while complex treatments for advanced diseases such as multiple sclerosis and cerebral palsy are more costly.

Below are some of the most popular uses of in treatments and their approximate costs.

👀 Watch a professional motocross racer share his experience with treatment for sports injuries and arthritis:

What are the advantages of therapy?

✅ Natural healing. therapy provides new hope for patients when conventional treatments have proven ineffective. It harnesses the body’s ability to repair and regenerate damaged tissues and promotes recovery at the cellular level.

✅ Versatility. can treat a wide range of conditions, from orthopedic injuries to chronic conditions, neurological disorders, and autoimmune diseases. The type and number of can be tailored to every patient, ensuring targeted treatment.

✅ Minimally invasive. therapies are usually delivered through simple injections or infusions, reducing the need for major surgery and allowing for quicker recovery.

How do doctors perform therapy?

Doctors perform therapies using several different administration methods, depending on the patient’s condition. Here are the most common types of administration:

1. Injection

One of the most common methods. Doctors inject directly into the affected area, such as a joint, muscle, or tendon. This method is minimally invasive and usually performed under local anesthesia.

🩹 Common uses: Joint pain, tendon injuries, arthritis, and soft tissue injuries.

2. Intravenous (IV) Infusion:

Doctors administer directly into the bloodstream via an IV. This allows the cells to circulate throughout the body and reach multiple sites that may need repair or regeneration.

🩹 Common uses: Autoimmune diseases, neurological disorders, and syic conditions like multiple sclerosis or diabetes.

3. Surgical implantation

For more complex or severe conditions, may need to be implanted directly into the affected tissue during surgery. Surgeons perform the procedure in an operating room under general anesthesia. 

🩹Common uses: Spinal cord injuries, severe heart disease, and advanced neurological conditions.

How much does therapy cost worldwide?

therapy costs vary widely depending on the country and the specific treatment involved. 

🗽 In the United States, the cost of injections can range between $20,000 to $50,000. However, other regions around the world offer more affordable options with high-quality care. 

🏰 In Europe, countries like Germany and the Netherlands offer high-quality regenerative medicine, but prices can be similar to those in the United States (from $7,500 to $50,000). Ukraine provides more affordable options between $4,000 and $15,000.

⛩️ In Asia, costs can range from $3,000 to $42,000, with South Korea being more expensive, while Thailand and Malaysia provide lower-cost alternatives.

🕌 In the Middle East, treatments cost anywhere from $2,000 to $35,000. Israel offers advanced regenerative therapies, while Turkey has more accessible prices.

Below is a table summarizing the cost of therapy in various countries:

🌍 Find out more about the countries with the best therapy clinics.

Does insurance cover therapy?

therapy is rarely covered by insurance because it is still considered experimental. Most insurance companies prefer to cover conventional treatments instead.

In the U.S., insurance typically only covers FDA-approved treatments. Currently, the FDA has approved the use of for treating blood cancers and immune disorders. However, as more evidence emerges from clinical trials and regulations evolve, insurance coverage for regenerative medicine might soon expand.

What are the best therapy clinics in the world?

Bookimed’s analysis of over 100 best clinics in the world has shown that Mexico, Turkey, and Thailand offer a perfect blend of affordable costs and high-quality care. In our rankings, we considered factors such as positive patient reviews, the number of patients treated, the speed of response, and the qualifications and accreditations of the clinics.

The table below highlights the top 7 treatment centers:

How to choose the best clinic?

Choosing the center for regenerative medicine involves careful consideration of several key factors. Here’s what to look for:

1. Accreditations and certifications. The treatment center should be accredited by recognized medical bodies like the Joint Commission International (JCI) or local health authorities.

2. Experience and expertise. Look for clinics with a proven track record in regenerative therapies. Check the qualifications and experience of the medical team, particularly in treating your condition.

3. Patient reviews. Read reviews from past patients to gauge the clinic’s reputation. Positive feedback on treatments, patient care, and overall experience is a good indicator of a clinic’s quality.

4. Safety and ethical standards. Verify that the center for regenerative medicine follows strict safety protocols and ethical standards, particularly in how they source and use . Avoid clinics that make unproven claims or lack transparency in their treatment procedures.

5. Cost and value. Compare costs between clinics and consider the value you are getting, including the quality of care, follow-up services, and additional support (e.g., accommodation, transfers).

6. Consultation and personalized care. A good center for regenerative medicine should offer a thorough consultation before any treatment. The availability of tailored treatment plans is a sign of a high-quality clinic.

7. Location and accessibility. Consider the clinic’s location if you need to travel. Ensure that the clinic is easily accessible and offers support for international patients, such as language assistance or travel arrangements.

What is the current status of research?

Regenerative medicine is still a relatively young field, and ongoing research is exploring its effectiveness for various diseases. The body of literature is already impressive. Here are only some of the latest breakthroughs from different clinical trials:

👉 Orthopedic conditions

• therapy can reduce chronic pain and improve motor function, with 70% of spinal injury patients experiencing significant improvements. 
• Sustained improvements in knee pain and function have been observed at the 24-month mark post-treatment.
• Improved joint function and reduced inflammation 1 to 3 years after treatment for rheumatoid arthritis (RA).

👀 Watch a patient review on the orthopedic treatment with :

👉 Autism

• 95% of patients improved their scores on the Childhood Autism Rating Scale (CARS). 
• In a notable case, a non-verbal child with severe autism began speaking and showed a 27% reduction in autism severity post-treatment.

👉 Heart failure

• A long-term 58% reduced risk of heart attack or stroke among heart failure patients.

👉 Eye diseases

• A 30-60% improvement in best corrected visual acuity (BCVA) in patients with inherited retinal diseases at 12 months after receiving treatment.

👉 Neurodegenerative diseases

• Amyotrophic lateral Sclerosis (ALS). Researchers have found that mesenchymal (MSCs) can slow down ALS progression.
• Multiple sclerosis (MS). therapy has proven more effective than traditional immunomodulatory drugs. It reduces inflammation and prevents excessive scarring in the nervous sy. The treatment suppresses MS activity for 4-5 years in 70-80% of patients.
• Parkinson’s disease (PD). Induced pluripotent (iPSCs) improve movement and increase rgic neurons in the brain.
• Alzheimer’s Disease (AD). treatments have shown a potential to improve AD patients' memory and learning abilities.
• Huntington’s disease (HD). MSCs improve motor function, stimulate neurogenesis, and reduce neuronal loss and abnormal protein levels.

How long does it take to see results?

The time it takes to see results from therapy varies depending on the patient and their condition.

🦴 For orthopedic issues, target localized areas of damage, allowing for faster regeneration of tissues like cartilage, which leads to quicker improvements. They may begin within a few weeks, with more noticeable results after 3 to 6 months. 

🧠 In neurological or chronic conditions, the healing process is more complex. Results may appear in several months, and gradual improvements may continue over a year or more. need more time to repair nerve or immune sy damage, so improvements take longer and progress gradually. 

💆🏻‍♀️ For aesthetic treatments, changes like skin or hair regeneration happen more quickly because the cells focus on surface-level repairs. Visible changes can be noticeable in a few weeks, with optimal results in a few months.

How long do results last?

therapy often leads to lasting improvements, but some patients may need follow-up treatments to maintain or enhance results over time. 

Various clinical studies have shown that improvements can last for extended periods—documented at 3, 6, 12, and 24 months after therapy. Research in conditions like rheumatoid arthritis and multiple sclerosis suggests that therapy can offer extended periods of symptom relief, with effects lasting 3–5 years.

Are there any possible risks and complications?

therapy is safe in most cases, but like any medical procedure, it carries potential risks and complications.

The most commonly reported side effects are:

• thromboembolism — occurs when a blood clot forms and blocks a blood vessel;
• fibrosis — the formation of excess scar tissue in an organ or tissue.

Other possible risks and complications include:

• infection — there’s a small risk of infection at the site of the injection or surgery, especially in more invasive procedures;
• rejection — in the case of donor , the body might recognize them as foreign and react;
• tumor formation — although extremely rare, certain have a theoretical risk of turning into tumors. Experienced doctors address this risk by carefully selecting and preparing the and closely monitoring patients. Reputable clinics use well-researched and tested , such as mesenchymal (MSCs), with a low risk of forming tumors.

To avoid complications and risks, clinics take preventive measures such as carefully screening , adhering to strict safety protocols, and closely monitoring the patient. 

By choosing a center for regenerative medicine from Bookimed’s trusted partners, you can be confident that you’ll receive specialized care with adherence to the highest safety standards.

How can you get treatment at the best center for regenerative medicine with Bookimed?

💚 Submit a request. Start by filling out a request on the Bookimed website. Share your medical details and preferences for therapy, so we can tailor our recommendations to your needs.

💚 Consult with a Bookimed Coordinator. Our manager will reach out to discuss your condition, answer any questions, and offer expert advice on therapies.

💚 Choose the best clinic. Based on your preferences, your Bookimed manager will recommend the centers for regenerative medicine. They'll help you compare options and make a well-informed decision.

💚 Receive a quote. Once you've selected a clinic, Bookimed will provide a customized cost estimate for your therapy.

💚 Schedule your trip. Bookimed will assist you in scheduling the therapy and planning your trip to the chosen regenerative medicine center. We ensure a smooth and hassle-free experience from start to finish.

Resources

1. Mayo Clinic. (2024). : What they are and what they do. https://www.mayoclinic.org/tests-procedures/bone-m-transplant/in-depth//art-20048117
2. WebMD. (2021). What Is Regenerative Medicine? https://www.webmd.com/a-to-z-guides/what-is-regenerative-medicine
3. Mayo Clinic. (2024). Study finds therapy is safe and may benefit people with spinal cord injuries. https://www.mayoclinic.org/medical-professionals/neurology-neurosurgery/news/study-finds--cell-therapy-is-safe-and-may-benefit-people-with-spinal-cord-injuries/mac-20567444
4. Medicine. (2020). Clinical efficacy and safety of therapy for knee osteoarthritis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7220405/
5. Regenerative Therapy. (2021). A review and update for registered clinical studies of for non-tumorous and non-hematological diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446785/
6. American Journal of . (2020). Cell transplantation as a novel therapeutic strategy for autism spectrum disorders: a clinical study. https://pubmed.ncbi.nlm.nih.gov/33489466/
7. European Review for Medical and Pharmacological Sciences. (2020). Autism treatment with : a case report. https://pubmed.ncbi.nlm.nih.gov/32767334/
8. Journal of the American College of Cardiology. (2023). Randomized Trial of Targeted Transendocardial Mesenchymal Precursor Therapy in Patients With Heart Failure. https://www.jacc.org/doi/10.1016/j.jacc.2022.11.061
9. Cell Research & Therapy. (2023). therapy for inherited retinal diseases: a syatic review and meta-analysis. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10557171/
10. Cellular and Molecular Neurobiology. (2023). The Use of as a Potential Treatment Method for Selected Neurodegenerative Diseases: Review. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10333383/