Treatment in Milan (Italy)

Prof. Carlo Castroro is the General Gastric and Esophagus Surgery Unit Director in Humanitas Research Hospital. He has graduated in the University of Padua and specialised in general medicine and thoracic surgery.

Medical areas of interest:

• gastric esophagus surgery
• day surgery
• general surgery

Previous experience:

Head of Simple Departmental Oncological Surgery Unit at the “Istituto Oncologico Veneto”, IOV - IRCCS, Padua.

Research areas of interest: 

• gastro-intestinal oncological surgery
• diseases of the esophagus with particular focus on oncologicy
• training, new technologies and distance learning
• day surgery and surgical services reorganization

Teaching experience: He is a professor in the Graduate School of General Surgery of the University of Padua and has also participated as a lecturer in numerous postgraduate training courses in the field of esophageal surgery, day surgery and minimally invasive surgery.

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=castoro+carlo

Dr. Paolo Casale is the Urology Unit Director in Humanitas Research Hospital. 

Medical areas of interest: 
his main focus is surgical treatment of oncological and functional diseases of the kidney, bladder and prostate.

He has developed a particular interest in conservative oncological surgery of the kidneys, both traditional and minimally invasive (laparoscopic and robotic), and has dedicated himself to the study of prostate and bladder oncological pathologies, with particular attention to the different urinary derivations, such as orthotopic neobladders.

Research areas of interest:
Surgical techniques in the treatment of kidney, bladder and prostate cancer.

Previous experience:

• 1999 – 2014 University Hospital of Pisa – Pisa (PI), Italy
  Medical Director at the Urology Unit 2 (Reference Center for Kidney tumors) headed by Dr. Francesco Francesca. Here he served as the organization and surgical training manager in the operating room of Residents in Urology and Students of Degree in Medicine and Surgery.
• He has also held the following positions: 
•  
• May 2012 – May 2013: Head of the Section of Professional interdisciplinary relevance of Robot-assisted Laparoscopic Surgery 
•  
• Nov 2008 – April 2012: Head of the Robot assisted Laparoscopic Surgery
•  
• 1994 – 2004: Research Fellow in Laparoscopic Surgery and Robotics at the Glickman Urological Institute at The Cleveland Clinic Foundation on advanced laparoscopic procedures, Robotic Surgery and Minimally Invasive Surgery – Cleveland – USA. (Chief: IS Gill).
•  
• December 1995 – May 1996: Research Fellow at the Department of Urology, Henry Ford Hospital – Detroit – Michigan – USA. (Chief: JO Peabody).
•  
• 1994: Clinical Internship at the Department of Urology, Montefiore Medical Center – Albert Einstein ​​University – New York – USA. (Chief: A. Mellman).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=casale p 

Prof. Salvatore Badalamenti is the Nephrology and Dialysis Unit Director in Humanitas Research Hospital. He has graduated at the Università degli Studi of Milan and is specialised in Medical Nephrology, Liver Diseases and Replacement.

Medical areas of interest:

• clinical nephrology and dialysis, chronic renal failure and its complications (anemia, osteodystrophy)
• preparation of vascular access for hemodialysis
• acid-base balance disorders. continuous renal replacement therapy in intensive care (CRRT)
• hepatorenal syndrome
• emergency medicine

Previous experience:

1990-1995 Polyclinic Hospital, Milan, Italy
He was a Staff grade specialist. Focused on infectious complications in dialysis treatments, particularly hepatitis C and anaemia, and nephrological and dialysis emergencies.

1986-1990 Provincial Hospital Clinic , Barcelona, Spain
He completed his PhD in Renal and Hepatic pathophysiology. Especially focused on the study of renal complications in patients with liver disease.

Research areas of interest: 

• clinical nephrology
• anemia and erythropoietin in renal failure and dialysis
• continuous renal replacement therapy in intensive care (crrt)
• hepatorenal syndrome. 
• phgosis and pentraxine in renal failure

He is a member of the Board of Directors of the Italian Society of Nephrology (SIN)

Teaching experience:

He is Professor of Internal Medicine and Emergency medicine and Professor of Nephrology at Università degli Studi of Milan.

Dott. Antonio Frontera is the Electrophysiology Unit Director in Humanitas Research Hospital.  

Medical areas of interest: 

After graduating in Medicine and Surgery at the University Cattolica del Sacro Cuore in Rome in 2006, he specialized in Cardiology at the same university in 2012.

Soon after his specialization he moved to England where he was hired as a Clinical and Research Fellow in cardiac electrophysiology at the Bristol Heart Institute (NHS), Bristol. 
He won a scholarship from the European Society of Aritmology (EHRA) and completed his training in cardiac electrophysiology at the prestigious Haut Léveque Hospital in Bordeaux, France, directed by Prof. Michel Haïssaguerre. In the same French university, he obtained his PhD.

During these 5 years of training abroad, he performed about 800 trans catheter ablation surgeries focusing mainly on the treatment of supraventricular arrhythmias. As a researcher, he has published nearly 100 scientific papers on innovation and trans catheter ablation techniques, defibrillator and pacemaker functioning algorithms.

Back to Italy, he was employed at the Aritmology Unit of the San Raffale Hospital specializing in the treatment of ventricular tachycardia, performing more than 150 procedures as a first and second operator.

To date, Dr. Frontera is the author of more than 145 scientific papers published in international journals. He constantly participates in national and international congresses of the sector.

Research areas of interest:
He has particular interest in the analysis of endocavitary signals (EGMs) in ventricular tachycardia and atrial fibrillation.

Thanks to a close collaboration with the Mathematics department of Politecnico di Milano, directed by Prof. Quarteroni, he studied innovative techniques for the treatment of complex arrhythmias.

Previous experience:
 

• Clinical and Research Fellow in Cardiac Electrophysiology - Bristol Heart Institute, Bristol, UK
• Clinical and Research Fellow in Cardiac Electrophysiology - Hôpital Haut Léveque, Bordeaux, FR

Publications: 

Sinus node exit, crista terminalis conduction, interatrial connection and wavefront collision: key features of human atrial activation in sinus rhythm.
Pambrun T, Derval N, Duchateau J, Ramirez FD, Chauvel R, Tixier R, Marchand H, Bouyer B, Welte N, André C, Nakashima T, Nakatani Y, Kamakura T, Takagi T, Krisai P, Ascione C, Balbo C, Cheniti G, Vlachos K, Bourier F, Takigawa M, Kitamura T, Frontera A, Meo M, Denis A, Sacher F, Hocini M, Jaïs P, Haïssaguerre M.Heart Rhythm. 2022 Jan 13

Electrogram fractionation during sinus rhythm occurs in normal voltage atrial tissue in patients with atrial fibrillation.
Frontera A, Limite LR, Pagani S, Cireddu M, Vlachos K, Martin C, Takigawa M, Kitamura T, Bourier F, Cheniti G, Pambrun T, Sacher F, Derval N, Hocini M, Quarteroni A, Della Bella P, Haissaguerre M, Jaïs P.Pacing Clin Electrophysiol. 2021

Slow Conduction Corridors and Pivot Sites Characterize the Electrical Remodeling in Atrial Fibrillation - ScienceDirect
Antonio Frontera MD, Ph.D1, Stefano Pagani Ph.D2, Luca Rosario Limite MD1, Andrea Peirone MD1, Francesco Fioravanti MD1, Bogdan Enache MD6, Jose Cuellar, MD4, Konstantinos Vlachos, MD5, Christian Meyer, MD, MA7, Giovanni Montesano, MD8, Andrea Manzoni, Ph.D2, Luca Dedè2 Ph.D2, Alfio Quarteroni, Ph.D2,3, Decebal Gabriel Lațcu, MD6, Pietro Rossi MD, Ph.D9, Paolo Della Bella MD1.
JACC EP Jan 2022

Right ventricular outflow tract electroanatomical abnormalities in asymptomatic and high-risk symptomatic patients with Brugada syndrome: Evidence for a new risk stratification tool?
Letsas KP, Vlachos K, Conte G, Efremidis M, Nakashima T, Duchateau J, Bazoukis G, Frontera A, Mililis P, Tse G, Cheniti G, Takigawa M, Pambrun T, Prappa E, Sacher F, Derval N, Sideris A, Auricchio A, Jais P, Haissaguerre M, Hocini M.J Cardiovasc Electrophysiol. 2021

Effect of electrode size and spacing on electrograms: Optimized electrode configuration for near-field electrogram characterization.
Takigawa M, Kitamura T, Basu S, Bartal M, Martin CA, Martin R, Cheniti G, Vlachos K, Pillois X, Frontera A, Massoullié G, Thompson N, Bourier F, Lam A, Duchateau J, Pambrun T, Denis A, Derval N, Cochet H, Haïssaguerre M, Sacher F, Hocini M, Jaïs P.Heart Rhythm. 2022 Jan;

Prof. Bruno Bernardini is the Neurological Rehabilitation Unit Director in Humanitas Research Hospital. 

Medical areas of interest:

Rehabilitation in acute-subacute phase of disabled patients for neurological diseases (stroke, cranial-encephalic and medullary trauma, tumors of the nervous sy, neuropathies). Hospital risk of fragile elderly patients. Orthogeriatrics.

Research areas of interest:
Post-operative rehabilitation indicators and process-outcome measures for patient prognostic stratification and clinical performance evaluation. 

He is the coordinator of a multicentre study for the application of process-outcome indicators in rehabilitation. The study involves hospital and extra-hospital facilities in Lombardy, Liguria and other regions of Central and Northern Italy.

Previous experience:

2005-2007 Galliera Hospital Authority, Genoa, Italy

Director of the Functional Recovery structure.

Member of the work group for defining the Regional Plan of rehabilitation work 2006-2009 in the Liguria region.

Evaluation, treatment and facilitation of care processes in patients in Neurology, Intensive Care, Neuro-surgery, Intermediate Care, Orthopaedic and Home Care. 

Outpatient work as a physiatric specialist, with a specific sector on the rehabilitation of the pelvic floor.

Development of processes in diagnostic and therapeutic hospital care (especially lumbar-sciatica, joint replacements, cardiac failure, femur fractures and most fast-track urological operations).

1988-1995 Hospital of Niguarda, Milan, Italy
Visiting doctor at the Centre for High Specialisation in Allergology and Clinical Immunology with full-time specialisation in the Department of Pneumology Piazza.

Teaching experience: Medicine Professor at the University of Genoa.

Scientific activities: Member of the board of directors and Geriatric area contact person at “Italian Urodynamic Society Continence, Neuro-Urology, Pelvic Floor”

Prof. Antonio Costanzo is the Dermatology Unit Director in Humanitas Research Hospital. He graduated with his MD degree in Medicine and Surgery from the University of Rome, La Sapienza in 1994. He then went on to complete post-graduate study and received a speciality degree in Internal Medicine in 1999 and a Dermatology speciality degree in 2006.

Medical areas of interest:

• Inflammatory and autoimmune skin diseases (Psoriasis, Atopic Dermatitis, Alopecia Areata, Chronic Urticaria, Suppurative Hydroadenitis, Scleroderma, Lupus)
• Personalized Medicine, Biological Psoriasis Therapy
• Dermatological Oncology (Melanoma, Actinic Keratosis, Basocellular and Spinocellular Epitheliomas).
• Prevention of skin neoplasms (dermatoscopy, computer mapping of moles).
• Dermatological surgery

Previous experience:

• Director of Dermatology Unit at Sant’Andrea Hospital in Vercelli
• University Researcher/Hospital Assistant at Tor Vergata Hospital 

Research areas of interest: 

• Psoriasis pathogenesis of other inflammatory and autoimmune skin diseases
• Pathogenesis of skin neoplasms
• Genetic disorders of the skin

His clinical research is focused on the characterization of the activity of biologics in psoriasis and psoriatic arthritis. This research is strictly linked to basic research activity on the pathogenesis of psoriasis and on the use of pharmacogenetic approach to predict the efficacy and safety of biologics in psoriasis.

In the past, Professor Costanzo has collaborated to the characterization of basic mechanisms of TNF inflammatory signalling in epithelial cells and NFkappaB regulation by different stimuli. More recently his research group has collaborated to the discovery of IL-21 as critical mediator of keratinocyte proliferation in psoriasis. Professor Costanzo has authored or co-authored more than 120 publications in internationally peer-reviewed journals.

Teaching experience: Full Professor of Dermatology at Humanitas University

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Costanzo+A 

Prof. Alessio Michele Goffredo Aghemo is the Hepatology Unit Director in Humanitas research Hospital.

Medical areas of interest: 

• liver diseases
• viral hepatitis
• metabolic hepatitis
• liver cirrhosis

Previous experience: 

From 2007 to 2017 he was the 1st level Medical Director at the U.O of Gastroenterology of the IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan.

Research areas of interest: 

Clinical and research activity focused on natural history and treatment of viral hepatitis.

He is the author of 155 peer-reviewed publications (Impact Factor total 1151.3, H-Index 25 according to Scopus, H-Index 20 last 5 years Scopus, H-Index 30 according to Google Scholar) (updated September 2017).

From 2013 to 2016 he was a scientific member of the governing board of the European Association for the Study of the Liver (EASL).

Since 2016 he is a member of the scientific committee of the European Association of Gastroenterology (UEG).

He is a member of the AISF (Italian Association for the Study of the Liver) commission for antiviral drugs directed against HCV (2012-present). Since 2016 he has been the coordinator of the same. 

He was AIFA/EMEA expert for liver disease since 2008.

Member of the Executive Committee of the HCV Regional Network, determined by the Lombardy Region on 28 September 2015.

He participated as an expert in the drafting of the European Guidelines 2013-2014-2015-2016-2017 (EASL) and Italian (AISF) on the Treatment of Chronic Hepatitis C.

Teaching experience:

He is associated professor of Gastroenterology at Humanitas University since September 2017.

Prof. Alessandro Castagna is the Orthopedic Surgery of the Shoulder and Elbow Unit Director in Humanitas Research Hospital. He performs both traditional surgeries and arthroscopic surgeries. He developed experience in arthroscopic surgery of the shoulder in the United States where he studied at the Southern California Orthopedic Institute, under the guidance of Dr. Stephen J. Snyder (famous shoulder surgeon, inventor and co-developer of surgical tools for shoulder arthroscopy).

Prof. Castagna gained experience in open surgery of the shoulder under the guidance of Prof. Mario Randelli, founder and past-president of the Italian Society for Surgery of the Shoulder, in Milan (Italy). He has specialized almost exclusively in shoulder surgery for more than 25 years and counts over 40.000 cases in his career. He carries out about 900 surgeries per year, including total shoulder prostheses, reverse prostheses, open and arthroscopic stabilization, rotator cuff repair and proximal humerus fractures.

Research areas of interest: 

Improvement of surgical and therapeutic methods of shoulder pathology. He gives particular attention to the study of biological and functional aspects with the development of surgical techniques, materials and dedicated tools. 

Teaching experience: Adjunct Professor at the Orthopedics Course of Specialization in Diseases of the Locomotor Sy at the University of L'Aquila.

Scientific activity: 

Prof. Castagna was president of European Society for Surgery of the Shoulder and the Elbow (ESSSE/SECEC) (www.secec.org) from 2012 to 2014 and president of Italian Society for Surgery of the Shoulder and Elbow (SICS&G) (www.sicseg.it) from 2010 to 2012. He is also a Member of the Board di International Congress of Shoulder and Elbow Surgery (ICSES, www.icses.org) nominated for the period from 2013 to 2022.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=castagna+alessandro

Prof. Alberto Albanese is the Neurology Unit Director at Humanitas Research Hospital. Until recently – Department Head of Neuroscience at the Institute of Neurology Carlo Besta (Milan). In 1977 prof. Albanese received his degree in medicine and surgery, in 1981 – in neurology, and in 1985 – in psychiatry. His professional experience began with the founding of the Department of “disorders of Parkinson’s and violations of the musculoskeletal sy” at the clinic “A. Gemelli “in Rome in 1984, which he led until 1996. From 1996 to 2000 prof. Albanese was the Head of the Neurological University Clinic of Lausanne (Switzerland) and a professor of Neurology in the University.

From 2000 to 2015 he was Head of Neuroscience Department at the Institute of Neurology Carlo Besta (Milan).

Prof. Albanese is a professor of neurology at the Institute of Neurology at the Catholic University of the Sacred Heart (Milan), Director of the post-graduate course “Diagnosis and treatment of movement disorders and degenerative neurological diseases” at the Foundation Neurological Institute “C. Besta”, as well as an adjunct professor at the School of Specialization in Neuroscience at the University of Milan Bicocca.

Prof. Albanese is the president of “Italian Association of Parkinson’s disease and movement disorders” and “Italian Association for the Study of the autonomic nervous sy” (which are part of “Italian Community of Neuroscience”). He is also an honorary member of the “French Community of Neuroscience.” The professor is a moderator and speaker at major national and international neurological conferences, he organized several symposia dedicated to Neurology, collaborates with numerous national and international research centers, which are studying Parkinson’s disease, movement disorders and degenerative neurological diseases. Prof. Albanese has been repeatedly receiving research fundings from the following government agencies: the Ministry of Health, Ministry of Science and Research, National Research Council, the British Council, the Swiss National Research Council.

He is one of the greatest Italian experts on the diagnosis and treatment of neurological diseases and movement disorders, Parkinson.

He has extensive experience in the use of neurostimulation of brain neurological movement disorders, for treating Parkinson’s disease and other involuntary movements.

He developed the first Italian project on the study of genetic disease and Parkinson’s dystonia, which led to the discovery of two new genetic loci. Also prof. Albanese is actively engaged in research in the field of semiotics detailed definition of involuntary movements, which allows tracking of related clinical pathology for accurate diagnosis of patients with movement disorders.

Prof. Albanese has published more than 200 scientific papers, most of which are published in indexed journals (with a total impact factor>500), is the author of one monograph, 3 books and co-author of numerous books and publications. He is the chief editor of “Frontiers in Movement Disorders” and assistant editor of the “European Journal of Neuroscience”.

Publications: http://www.ncbi.nlm.nih.gov/pubmed?term=albanese a

Dr. Maurizio Fornari is the Head of the Neurosurgery Unit in Humanitas Research Hospital.

After his specialization in neurosurgery in 1979 at the University of Milan, Dr. Fornari has followed courses in neurosurgery at Mount Sinai Hospital, New York (USA) and advanced courses in Spinal Surgery and skull base at the Center St. Louis (USA) and the Center of Albuquerque (USA).

Dr. Fornari specializes in the treatment of all major diseases of the central and peripheral nervous sy, from the compression of the spinal nerves (lumbar and cervical disc hernias, stenosis of the cervical canal, instability of the spine, spinal cord tumors), primary and secondary brain tumors, to congenital malformations of the central nervous sy. Dr. Fornari is a recognized leader in the development of computer assisted spine surgery.

Dr. Fornari is a recognized leader in the development of minimally invasive surgery, who among the first has adopted bloodless methods such as micro decompression with unilateral approach for the treatment of lumbar stenosis instead of the much more invasive laminectomy.

Another dreaded disease, sometimes associated with stenosis or lumbar spondylolisthesis, which Dr. Fornari is approaching for quite a long time with the help of spinal navigation sys and intraoperative CT scan, which helps the work of the surgeon during the intervention, reducing invasiveness and risks for the patient, represent lumbar instability.

He and his team perform more than 1.300 surgeries a year, and he has one of the most important case studies in the world (data from a few years ago published in the Journal of Neurosurgery: 
http://thejns.org/action/doSearch?displaySummary=false&AllField=maurizio+fornari.) 

Since 2012, he teaches at the University of Milan. He is also Assistant Editor of "Advanced Technology in Neurosurgery" published by Sprinter Verlag Berlin Heldelberg (1988).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=fornari%m

Prof. Dr. Maria Grazia Bordoni is the Vascular Surgery Unit Director in Humanitas Research Hospital. She has graduated at Università degli Studi of Milan and specialised as a vascular surgeon and since then she has been interested in vascular surgery in all its aspects.

Medical areas of interest:

Her main specialties are endovascular surgery and treatment of the large vessels of the abdomen and thorax (aorta, thoracic cavity), carotid surgery, endovascular and surgical treatments for arteries of the lower limbs, preparation of complex vascular access in hemodialysis, phlebology, diagnosis and treatment of vascular malformations. 

Research areas of interest: 

When it comes to the research activity, Dr. Bordoni is mainly dealing with early treatment of acute ischemic strokes and stimulation of the carotid baroreceptors in patients with heart failure. Prof. Bordoni has performed more than 2000 surgeries as first surgeon in her Humanitas career. 

Since 2005, she is also Milan University professor: she teaches General Surgery and focuses on the topic of vascular and surgical emergencies.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=bordoni+mg

Dr. Marco Grimaldi is the Diagnostic Neuroradiology Unit Director in Humanitas Research Hospital.

Medical areas of interest:

• magnetic resonance
• computed tomography
• angiography of the central nervous sy, brain and spine
• study of the brachial plexus
• functional neuroradiology, in particular, study of cerebral perfusion for perfusion CT related to problems in an emergency regime
• spine dimorphism, in particular of the paediatric age and in rare diseases

He has developed full diagnostic, organizational and managerial autonomy of any problem in outpatient, hospital and emergency neuroradiology.

Research areas of interest:

• Functional imaging studies on coma
• Diagnosis and development of prognostic algorithms
• Research and development, even experimental, of new applications related to technological developments (research on new protocols for the use of the Multidetector Computed Tomography (MDCT), for the use of perfusion CT in vascular and emergency environments finally, study of the trachea in patients at risk of anesthesiology).

Previous experience:

1990 – 2012 Neuroradiologist at Hospital of San Gerardo in Monza, Italy

He was the Director on highly specialised activities related to functional neuroradiology. 

He worked in diagnostic autonomy, organization and management of any problem within neuroradiological outpatient, inpatient and emergency context. 

He is particularly interested in the field of functional neuroradiology, in research and experimental development of new applications also tied to technological developments and creation of new protocols for use of MDCT (use of CT perfusion imaging in the field of vascular and urgency. He was involved in the study of the trachea in patients at high anaesthetic risk), in paediatric radiology with particular reference to diagnosis and clinical management of rare diseases (consultant in the Outpatient Unit for metabolic diseases and in the Outpatient Unit for rare and genetic diseases at the Hospital). He is also interested in the study of problems related to the craniocervical junction.

Teaching experience: 

From 2002 to 2012 he has been a professor at Milano-Bicocca University of Milan.

From 2002 to 2012 : Professor of the courses "Technique and diagnostics for images I", "Technique and diagnostics for images II" and "Semeiotics neuroradiological CT" for the degree in Medical Radiology for Images and Radiotherapy.
From 2003 to 2012: Professor of the course "Functional Brain Diagnostics" for the Degree in Physiotherapy. 
From 2003 to 2012: Professor for the Degree Course in Neurotherapy and psychomotricity of the developmental age.
From 2006 to 2009: Lecturer at the School of Specialization in Radiodiagnostics.

Prof. Guido Grappiolo is Orthopedics Hip and Prosthesis Unit Director in Humanitas Research Hospital. Since 1991, Prof. Guido Grappiolo began working as a researcher dedicated mainly to hip surgery in cooperation with internationally renowned authors such as: Prof. Ganz Prof. T. Gruen, Prof. D. Blaha (U.S.A.), Prof. H. Wagner (Germany), Prof. E. Morscher (Switzerland).

He collaborates with major international schools in the research of new and modern strategies in the field of minimally invasive prosthetics, computer-assisted surgery and conservative surgery. To encourage research in orthopedics is the main scientific goal of the establishment and organization of the "Foundation Livio Sciutto – NPO", an organization of which Prof. Grappiolo is the scientific director. Playing this role, Prof. Grappiolo has been creating and maintaining contacts with other national and international research institutes, which trained thousands of surgeons coming from every country of the world.

The organization has one of the largest hip replacement database of the world: more than 45.000. Dr. Grappiolo is mentored by Dr. Spotorno (a master and pioneer in prosthetic surgery), and their group studied and developed some of the bestselling prosthesis in the world. His research led him to contact the major international schools with which he collaborates in the search for new strategies of improvement in prosthetic minimally invasive and computer-assisted conservative surgery with the development of new prosthetic models and exploration of new materials.

To date, he has attended over 170 meetings, both national and international, almost every time in the role of speaker or chairman. His name appears as author, in more than 60 publications and articles. He has performed more than 2600 prosthetic surgery (hip, knee and ankle).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=grappiolo

Prof. Giorgio Walter Canonica is the Head of Personalized Medicine Center: Asthma and Allergy in Humanitas Research Hospital.

Medical areas of interest:
Asthma and allergies 

Research areas of interest: 
T cells: study of different subgroups and their functional role in basic and clinical research (allergy, specific autoimmunity of organs, degenerative diseases of the CNS and cancer).

Molecular events and interactions between immunocompetent cells, inflammatory cells, epithelial cells in allergic inflammation and airway remodelling.

Biomarkers that define the therapeutic response in asthma.

New antiallergenic drugs and new strategies in the treatment of allergic disease.

Clinical and immune-pharmacological activities of modifiers of biological responses such as cytokines, monoclonal antibodies, specific immunotherapy for allergens, etc.

Results of reported patients and assessment of quality of life in patients with respiratory and allergic diseases.

Prof. Canonica coordinated and conducted more than 50 tests (phase II-IV) according to current GCP rules (certification number 2426574, 29/06/2017).

He has also served as an arbitrator for most of the most important international journals - Editor-in-Chief of "Current Opinion in Allergy and Clinical Immunology" – Associated Editor "Annals of Allergy & Clinical Immunology".

Previous experience:
Director of the Degree programme of Lung Diseases at the University of Genoa (1998 - Today) President of the Clinic for Diseases of Allergies and Respiratory - Department of Internal Medicine, University of Genoa - IRCCS AOU San Martino IST

(1997) Director of the Specialized School of Allergy and Clinical Immunology DIMI, University of Genoa

• (1998-present) Full professor of allergies and respiratory diseases, Department of Internal Medicine, University of Genoa
   
• (1995-1998) Full professor of Internal Medicine, Department of Internal Medicine, University of Genoa
   
• (1982) Associate Professor Allergy and Clinical Immunology-Dept. of Internal Medicine
  (1977) Assistant Professor of Internal Medicine - University of Genoa
• (1973) Assistant at the Clinic of Pulmonary Diseases - University of Genoa

Publications:

https://www.ncbi.nlm.nih.gov/pubmed/?term=giorgio+walter+canonica

Dott. Federico Della Rocca is the Prosthetic and Minimally Invasive Hip and Knee Orthopaedics. 

Medical areas of interest: 
Pathology of the hip and knee, with particular interest in prosthetic and arthroscopic hip surgery. He performs about 700 surgeries every year. He has numerous participations as speaker at national and international conferences.

Previous experience:
He was an attending physician at Steadman Hawkins Clinic Hospital, Vail Colorado, USA. 

He gave a great contribution to the development of the GTS (Global Tissue Sparing) hip prosthetic and biomechanical rotational stability tests with Prof Thomsen, Heidelberg (Germany) 12/2012.

Research areas of interest: 
Arthroscopic techniques on the hip

Teaching experience: 
Theory and practical courses in arthroscopic and prosthetic hip surgery at Medical Education

Prof. Luca Balzarini is the head of the Department of Diagnostic Imaging in Humanitas Research Hospital. He lectured at the post-graduation school in Radiology at the University of Milan and Pavia and he is member of the European Society of Radiology and of the Italian Society of Medical Radiology (SIRM).
He graduated cum laude in Medicine and Surgery at the University of Milan in 1982 and in 1986 he graduated cum laude at the post-graduation school of Radiology at the University of Milan.

His career started at Istituto Nazionale dei Tumori in Milano where he attended as a PHD student of the University of Milan.
After a long experience abroad, where he developed master expertise in Magnetic Resonance Imaging, he then became Assistant in the Department of Diagnostic radiology at Istituto Nazionale dei Tumori (IRCCS) in Milan where he has this role for 12 years now.

Since 1997 he has been working at Humanitas Research Hospital as head of Magnetic Resonance Section, and then head of Diagnostic Radiology Unit (2006). Nin 2012 he became head of Department of Diagnostic Imaging.

In his high technology Department there are 5 MRI machines (from 1 up to 3 T units), 4 CT scans, and an angiography suite, all radiological techniques are regulated by a sy of dose control (Dose Watch).

His team, composed of 25 radiologists, has recognized expertise in several fields of Diagnostic and Interventional Imaging and particularly dedicated in Oncological, Muscle-Skeletal, Neuro and Cardiac Imaging.

Prof. Marco Alloisio is the thoracic surgery Unit Director at Humanitas Research Hospital. He graduated in Medicine in 1976 at Università Statale of Milan, specialized in General Surgery, Oncological and Thoracic Surgery. 

Under the guidance of Professor Umberto Veronesi, from 1977 to 1997 he was an assistant in the divisions of general oncological, otolaryngology and thoracic surgery at the National Cancer Institute of Milan (INT). During this period, he also worked with general surgery, breast surgery, oncological otorhinolaryngology and had several periods spent studying abroad (Paris and New York at the Memorial Sloan Kettering Cancer Center).

In 1997 he started his activity at Humanitas Research Hospital and in 1998 he was appointed Chief of Mini-Invasive Thoracic Surgery. From 2006 he was designated Chief of Thoracic Surgery at the same Institution. Main clinical activity has been focused on Thoracic Surgical Oncology, and in particular all kinds of surgical management of primary and secondary lung cancer, lung metastases, mediastinal tumors and thoracic wall tumors. Prof. Marco Alloisio is president of the Italian League for the fight against cancer (LILT) in Milan, and member of many national and international societies (SIC, SICO, ESSO, ISDE, ACOI, SICT, ESTS).

Author of over 200 publications, including articles and presentations to national and internationals scientific meetings. His engagement in clinical research involves early detection and management of primary lung cancer and his treatment also with video-assisted techniques, successful treatment of lung metastases with new techniques for salvage surgery (multiple sub lobar resections and laser resections) but also aggressive surgery for advanced lung cancers after induction chemotherapy and treatment of the thoracic wall and vertebral bodies. 
In the latter field, he is engaged in the surgical treatment of malignant pleural mesothelioma (extra pleural pneumonectomy) with multimodality approaches in a multicentric Italian cooperative group.

Currently engaged in genetic research studies such as "ERCC1 and B-Tubulin exspression in locally advanced NSCLC treated with platinum/vinorelbin neodjuvant chemotherapy" and in external collaborations with universities and hospitals around the world.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=alloisio+marco

Prof.  Marco Francone is the Cardiovascular Imaging Unit Director in Humanitas Research Hospital.

Medical areas of interest:

Imaging in cardiovascular and pulmonary diseases

Previous experience:

- First level Medical Director at the Department of Radiological, Oncological and Anatomy-Pathological Sciences, at Policlinico Umberto I in Rome

- Past-President, Cardiology Section at the Italian Society of Medical Radiology (SIRM)

Research areas of interest: 

Inflammatory heart disease, cardiomyopathy, imaging of acute myocardial infarction, imaging in cardio-toxicity, imaging of post-COVID patients.

Prof.  Marco Francone is the author of more than 150 indexed scientific papers with an impact factor of more than 500 and has lectured around the world for fifteen years, from the United States to Asia, from Africa to Australia.

Teaching experience:

Full Professor of Radio diagnostics at Humanitas University

Publications:

https://pubmed.ncbi.nlm.nih.gov/?term=marco+francone&sort=pubdate&size=200&show_snippets=off