Treatment in Milan (Italy)

Prof. Leonardo Maradei is specialised in orthopaedics and traumatology and is the Director of the Foot Surgery and Minimally Invasive Operations Unit in Humanitas Research Hospital. 

Prof. Leonardo Maradei performs surgery on the foot with minimally invasive techniques and arthroscopic surgery. After his specialization he deepened his studies in arthroscopic surgery of the shoulder and the knee at the Mississippi Sports Medicine & Orthopaedic Center (USA), under the guidance of prof. F. H. Savoie. He has developed considerable experience in shoulder prosthetic surgery as a pupil of prof. Mario Randelli. 
His research is focused on the development of new prosthetic materials for the shoulder. During his years in Humanitas he has performed more than 2000 surgeries on the foot, more than 1000 on the knee and more than a 1000 on the shoulder. 

Dr. Maradei is a professor at Università Statale of Milan where he teaches Medicine and Surgery - Lessons on minimally invasive surgery of the shoulder and knee.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=maradei+leonardo

Prof. Marco Montorsi is the Director of the Department of General and digestive surgery unit in Humanitas Research Hospital and he is Professor of General Surgery at the Humanitas University. His academic career started in the the Humanitas University of Milan, where he entered in 1980 as Assistant Professor and was appointed as Professor of Surgery in 2001.

His main interests are in the field of digestive diseases and in the surgical treatment of the related pathologies, mainly hepatico-pancreatico-biliary (HPB) and colorectal pathologies. He is indeed the Director of the Department of Surgery in Humanitas Research Hospital where a great volume of major abdominal surgeries is routinely performed. Around 250 -300 hepatic and pancreatic resections and 350 colorectal resections.
He began performing laparoscopic colorectal surgery in the early 90s and gained a lot of experience in this field. The vast majority of colorectal tumours diagnosed in the department of Surgery is submitted to laparoscopic resection thus allowing a smooth and safe disease course. A robotic approach with the new Da Vinci equipment is now available for patients with rectal tumours.

Transanal endoscopic microsurgery (TEM) with dedicated instruments is also offered to selected patient with low-sited rectal tumours so sparing major abdominal approach.

A routine policy of strict interaction with the Dept. of Oncology is active for patients needing a perioperative chemo- and radiotherapy with the aim of full integration for a better care and results.

Prof. Marco Montorsi is also Humanitas University President with over 10 years of experience in didactic and clinic teaching to medical students.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=montorsi+marco

Prof. Romano Lutman is the Head Oncological and interventional radiology Unit.

Medical areas of interest: 
diagnostic and interventional oncology, in particular linked to percutaneous imaging-guided procedures.
He has performed over 3000 CT guided lung biopsies and numerous international trials on anticancer drugs.

Research areas of interest: 
advanced oncological diagnostics. Percutaneous minimally invasive imaging-guided diagnostic and therapeutic procedures in oncology.

Previous experience:  
- 1991-1996 Orthopaedic Institute of Gaetano Pini, Italy
Assistant Physiatrist
- 1991-1991 Hospital of the Piemonte region , Italy
Specialist doctor in sports medicine

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=lutman r

Prof. Antonio Costanzo is the Dermatology Unit Director in Humanitas Research Hospital. He graduated with his MD degree in Medicine and Surgery from the University of Rome, La Sapienza in 1994. He then went on to complete post-graduate study and received a speciality degree in Internal Medicine in 1999 and a Dermatology speciality degree in 2006.

Medical areas of interest:

• Inflammatory and autoimmune skin diseases (Psoriasis, Atopic Dermatitis, Alopecia Areata, Chronic Urticaria, Suppurative Hydroadenitis, Scleroderma, Lupus)
• Personalized Medicine, Biological Psoriasis Therapy
• Dermatological Oncology (Melanoma, Actinic Keratosis, Basocellular and Spinocellular Epitheliomas).
• Prevention of skin neoplasms (dermatoscopy, computer mapping of moles).
• Dermatological surgery

Previous experience:

• Director of Dermatology Unit at Sant’Andrea Hospital in Vercelli
• University Researcher/Hospital Assistant at Tor Vergata Hospital 

Research areas of interest: 

• Psoriasis pathogenesis of other inflammatory and autoimmune skin diseases
• Pathogenesis of skin neoplasms
• Genetic disorders of the skin

His clinical research is focused on the characterization of the activity of biologics in psoriasis and psoriatic arthritis. This research is strictly linked to basic research activity on the pathogenesis of psoriasis and on the use of pharmacogenetic approach to predict the efficacy and safety of biologics in psoriasis.

In the past, Professor Costanzo has collaborated to the characterization of basic mechanisms of TNF inflammatory signalling in epithelial cells and NFkappaB regulation by different stimuli. More recently his research group has collaborated to the discovery of IL-21 as critical mediator of keratinocyte proliferation in psoriasis. Professor Costanzo has authored or co-authored more than 120 publications in internationally peer-reviewed journals.

Teaching experience: Full Professor of Dermatology at Humanitas University

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Costanzo+A 

Prof. Carlo Castroro is the General Gastric and Esophagus Surgery Unit Director in Humanitas Research Hospital. He has graduated in the University of Padua and specialised in general medicine and thoracic surgery.

Medical areas of interest:

• gastric esophagus surgery
• day surgery
• general surgery

Previous experience:

Head of Simple Departmental Oncological Surgery Unit at the “Istituto Oncologico Veneto”, IOV - IRCCS, Padua.

Research areas of interest: 

• gastro-intestinal oncological surgery
• diseases of the esophagus with particular focus on oncologicy
• training, new technologies and distance learning
• day surgery and surgical services reorganization

Teaching experience: He is a professor in the Graduate School of General Surgery of the University of Padua and has also participated as a lecturer in numerous postgraduate training courses in the field of esophageal surgery, day surgery and minimally invasive surgery.

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=castoro+carlo

Prof.  Roberto Gatti is the Physiotherapy Unit Director in Humanitas Research Hospital. Prof. Roberto Gatti became physiotherapist in 1985 at the University of Milan (Italy). In 1996 he got the licénce en kinésithérapie et réadaptation  at the Catholique University of Louvain la Neuve (Belgium) and, in 2009, the Master of sciences in Rehabilitation Sciences at the University of Florence (Italy).

Medical areas of interest: 

motor rehabilitation

Previous experience:
 

Didactic coordinator of Physiotherapy degree programme of the Vita-Salute San Raffaele University

• Group Leader of the Motor Function Analysis and Rehabilitation Laboratory of the Department of Neuroscience of San Raffaele Hospital
• Head of physiotherapy at San Raffaele Hospital

Research areas of interest:

Research lines of Prof. Roberto Gatti are mainly addressed on Biomechanics and Neurorehabilitation, with a focus on the effects of cognitive facilitations (i.e. action observation) on motor relearning of subjects with lesion at the central nervous system. As Biomechanics research lines his interest is focused on the study of anticipatory postural adjustments and their coordination with the agonist component of movement.

Teaching experience: 

Associated Director of the Physiotherapy degree programme of Humanitas Research Hospital since 2016

Prof. Enrico Arnaldi is the Arthroscopic and Reconstructive Surgery of the Knee Unit Director in Humanitas Research Hospital. 
He was the medical apprentice of Dr. Lorenzo Spotorno (a master and pioneer in prosthetic surgery). Since 1984, he has dedicated himself to arthroscopic knee surgery and later on shoulder surgery.

Medical areas of interest: He is specialized in degenerative and post-traumatic shoulder diseases (rotator cuff tendon injuries, glenomeral arthrosis, shoulder instability) and related surgical treatments, arthroscopic (tendon repairs, capsuloplasty, etc.) and open (latarjet stabilization, orthoprosthesis, etc.). 
He also deals with degenerative and post traumatic knee pathologies, with particular attention to the osteoarthritis of the knee (primitive or secondary), the post-traumatic complex capsule-ligamentous instabilities, the lesions of the cruciate ligaments, meniscus and cartilage, and open-air surgical treatments (such as corrective osteotomies, first implant orthoprosthesis and revisions) and arthroscopic (meniscectomies and meniscal sutures, meniscal transplants, ACL reconstruction, treatment of focal cartilage lesions). 

Research areas of interest:
There are many research interests, ranging from biotechnology to meniscal transplants and osteochondral grafts, from allogeneic grafts for reviews from failures of ligamentous reconstruction to patella stabilization.

He practiced his specialty in the US in some of the world-renowned medical institutions along with internationally famous doctors: the University of Pittsburgh (Dr. Freddie Fu, Dr. Harner, Dr. Savio Lee Wo), the Intermountain Hospital in Salt Lake City (Dr. Rosemberg, Dr. Paulos), Dr. E. Wolf (San Francisco), Dr. Helman and Dr. Morrison (Los Angeles), Dr. Nottage, Dr. Esch (San Diego), Dr. Steadman and Dr. Hawkins (Vail), Dr. P. Fowler (London Ontario Canada), and J. P. Warner in Boston University.

He has performed more than 10,000 arthroscopic knee surgeries and approximately 1,200 prosthetic reconstruction of the knee. He has always been very involved in the research works in the area of new biotechnologies, meniscal and osteochondral transplantation, allogeneic grafts for revisions by failures of ligament reconstructions, stabilization of the patella.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=arnaldi+enrico

Dr. Maurizio Fornari is the Head of the Neurosurgery Unit in Humanitas Research Hospital.

After his specialization in neurosurgery in 1979 at the University of Milan, Dr. Fornari has followed courses in neurosurgery at Mount Sinai Hospital, New York (USA) and advanced courses in Spinal Surgery and skull base at the Center St. Louis (USA) and the Center of Albuquerque (USA).

Dr. Fornari specializes in the treatment of all major diseases of the central and peripheral nervous system, from the compression of the spinal nerves (lumbar and cervical disc hernias, stenosis of the cervical canal, instability of the spine, spinal cord tumors), primary and secondary brain tumors, to congenital malformations of the central nervous system. Dr. Fornari is a recognized leader in the development of computer assisted spine surgery.

Dr. Fornari is a recognized leader in the development of minimally invasive surgery, who among the first has adopted bloodless methods such as micro decompression with unilateral approach for the treatment of lumbar stenosis instead of the much more invasive laminectomy.

Another dreaded disease, sometimes associated with stenosis or lumbar spondylolisthesis, which Dr. Fornari is approaching for quite a long time with the help of spinal navigation systems and intraoperative CT scan, which helps the work of the surgeon during the intervention, reducing invasiveness and risks for the patient, represent lumbar instability.

He and his team perform more than 1.300 surgeries a year, and he has one of the most important case studies in the world (data from a few years ago published in the Journal of Neurosurgery: 
http://thejns.org/action/doSearch?displaySummary=false&AllField=maurizio+fornari.) 

Since 2012, he teaches at the University of Milan. He is also Assistant Editor of "Advanced Technology in Neurosurgery" published by Sprinter Verlag Berlin Heldelberg (1988).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=fornari%m

Prof. Dr. Maria Grazia Bordoni is the Vascular Surgery Unit Director in Humanitas Research Hospital. She has graduated at Università degli Studi of Milan and specialised as a vascular surgeon and since then she has been interested in vascular surgery in all its aspects.

Medical areas of interest:

Her main specialties are endovascular surgery and treatment of the large vessels of the abdomen and thorax (aorta, thoracic cavity), carotid surgery, endovascular and surgical treatments for arteries of the lower limbs, preparation of complex vascular access in hemodialysis, phlebology, diagnosis and treatment of vascular malformations. 

Research areas of interest: 

When it comes to the research activity, Dr. Bordoni is mainly dealing with early treatment of acute ischemic strokes and stimulation of the carotid baroreceptors in patients with heart failure. Prof. Bordoni has performed more than 2000 surgeries as first surgeon in her Humanitas career. 

Since 2005, she is also Milan University professor: she teaches General Surgery and focuses on the topic of vascular and surgical emergencies.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=bordoni+mg

Dr. Marco Grimaldi is the Diagnostic Neuroradiology Unit Director in Humanitas Research Hospital.

Medical areas of interest:

• magnetic resonance
• computed tomography
• angiography of the central nervous system, brain and spine
• study of the brachial plexus
• functional neuroradiology, in particular, study of cerebral perfusion for perfusion CT related to problems in an emergency regime
• spine dimorphism, in particular of the paediatric age and in rare diseases

He has developed full diagnostic, organizational and managerial autonomy of any problem in outpatient, hospital and emergency neuroradiology.

Research areas of interest:

• Functional imaging studies on coma
• Diagnosis and development of prognostic algorithms
• Research and development, even experimental, of new applications related to technological developments (research on new protocols for the use of the Multidetector Computed Tomography (MDCT), for the use of perfusion CT in vascular and emergency environments finally, study of the trachea in patients at risk of anesthesiology).

Previous experience:

1990 – 2012 Neuroradiologist at Hospital of San Gerardo in Monza, Italy

He was the Director on highly specialised activities related to functional neuroradiology. 

He worked in diagnostic autonomy, organization and management of any problem within neuroradiological outpatient, inpatient and emergency context. 

He is particularly interested in the field of functional neuroradiology, in research and experimental development of new applications also tied to technological developments and creation of new protocols for use of MDCT (use of CT perfusion imaging in the field of vascular and urgency. He was involved in the study of the trachea in patients at high anaesthetic risk), in paediatric radiology with particular reference to diagnosis and clinical management of rare diseases (consultant in the Outpatient Unit for metabolic diseases and in the Outpatient Unit for rare and genetic diseases at the Hospital). He is also interested in the study of problems related to the craniocervical junction.

Teaching experience: 

From 2002 to 2012 he has been a professor at Milano-Bicocca University of Milan.

From 2002 to 2012 : Professor of the courses "Technique and diagnostics for images I", "Technique and diagnostics for images II" and "Semeiotics neuroradiological CT" for the degree in Medical Radiology for Images and Radiotherapy.
From 2003 to 2012: Professor of the course "Functional Brain Diagnostics" for the Degree in Physiotherapy. 
From 2003 to 2012: Professor for the Degree Course in Neurotherapy and psychomotricity of the developmental age.
From 2006 to 2009: Lecturer at the School of Specialization in Radiodiagnostics.

Dott. Federico Della Rocca is the Prosthetic and Minimally Invasive Hip and Knee Orthopaedics. 

Medical areas of interest: 
Pathology of the hip and knee, with particular interest in prosthetic and arthroscopic hip surgery. He performs about 700 surgeries every year. He has numerous participations as speaker at national and international conferences.

Previous experience:
He was an attending physician at Steadman Hawkins Clinic Hospital, Vail Colorado, USA. 

He gave a great contribution to the development of the GTS (Global Tissue Sparing) hip prosthetic stem and biomechanical rotational stability tests with Prof Thomsen, Heidelberg (Germany) 12/2012.

Research areas of interest: 
Arthroscopic techniques on the hip

Teaching experience: 
Theory and practical courses in arthroscopic and prosthetic hip surgery at Medical Education

Prof. Guido Grappiolo is Orthopedics Hip and Prosthesis Unit Director in Humanitas Research Hospital. Since 1991, Prof. Guido Grappiolo began working as a researcher dedicated mainly to hip surgery in cooperation with internationally renowned authors such as: Prof. Ganz Prof. T. Gruen, Prof. D. Blaha (U.S.A.), Prof. H. Wagner (Germany), Prof. E. Morscher (Switzerland).

He collaborates with major international schools in the research of new and modern strategies in the field of minimally invasive prosthetics, computer-assisted surgery and conservative surgery. To encourage research in orthopedics is the main scientific goal of the establishment and organization of the "Foundation Livio Sciutto – NPO", an organization of which Prof. Grappiolo is the scientific director. Playing this role, Prof. Grappiolo has been creating and maintaining contacts with other national and international research institutes, which trained thousands of surgeons coming from every country of the world.

The organization has one of the largest hip replacement database of the world: more than 45.000. Dr. Grappiolo is mentored by Dr. Spotorno (a master and pioneer in prosthetic surgery), and their group studied and developed some of the bestselling prosthesis in the world. His research led him to contact the major international schools with which he collaborates in the search for new strategies of improvement in prosthetic minimally invasive and computer-assisted conservative surgery with the development of new prosthetic models and exploration of new materials.

To date, he has attended over 170 meetings, both national and international, almost every time in the role of speaker or chairman. His name appears as author, in more than 60 publications and articles. He has performed more than 2600 prosthetic surgery (hip, knee and ankle).

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=grappiolo

She performs interventions for the establishment of distal arteriovenous fistulas in collaboration with the vascular surgeon and autonomously performs procedures of tunneled CVC placements for the execution of the dialysis treatment.

Collaborates with intensive care units and coronary arteries for continuous dialysis treatments (CRRT) in patients with acute renal failure and chronic dialysis patients.

She manages the Centre of clinical nephrology and dialysis at San Donato Hospital with particular interest in conservative therapy and pre-dialysis.

After receiving his Medical Degree, Board Certification in Allergy and Clinical Immunology, and PhD in Basic and Applied Immunology, Dr. Della Torre worked for 3 years in the United States at the “Ragon Institute of Massachusetts General Hospital (MGH), Massachusetts Institute of Technology (MIT), and Harvard Medical School” in Boston. Thanks to a Cariplo Foundation research grant, Dr. Della Torre returned to Italy in 2018 and established his lab within the Division of Genetic and Cell Biology of San Raffale Hospital (Milan, Italy).

Dr. Della Torre is now Assistant Professor of Rheumatology at Vita-Salute San Raffaele University and Senior Consultant at the Unit of Immunology, Rheumatology, Allergy, and Rare Disease (UnIRAR) of San Raffaele Hospital.

Dr. Della Torre authored more than 100 scientific publications on international peer-reviewed journals and achieved prestigious awards such as the Collegio Ghislieri and the Cariplo Foundation awards for young researchers, the TRIDEO award, the MyFirst AIRC research grant, and the Career Research Grant Award from the FOREUM Foundation.

With his seminal works Dr. Della Torre contributed to the characterization of a novel autoimmune disease known as “IgG4-related disease” and is currently considered “World Expert of IgG4-related disease” by the prestigious Expertscape platform.

Dr. Della Torre is the Disease Coordinator of the IgG4-related disease European working group of the European Reference Network (ERN) on Rare Connective Tissue and Musculoskeletal Diseases (ReCONNET).

Up to September 2022, his scientific publications received more than 6000 citations with an H-index of 35.

Dr. Della Torre presented his studies in different national and international immune-rheumatologic congresses, organized a number of scientific meetings, and co-authored 10 medical books. He presently serves as reviewer for more than 50 peer-reviewed journals and as associated editor for three international scientific journals. Dr. Della Torre is a Head of the:

• IgG4-Related Disease Clinic
• Autoimmune pancreatitis Clinic
• Retroperitoneal Fibrosis Clinic at San Raffaele Hospital (Milan, Italy)