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Professor Antonino Spinelli is the Director of the Division of Colon and Rectal Surgery at Humanitas Research Hospital.

The Division of Colon and Rectal Surgery is one of the most important centres for colorectal disease, especially for procedures of sphincter preservation for rectal tumours, but also for chronic inflammatory bowel disease (Crohn disease, ulcerative rectal colitis…) and the surgical treatment of diverticular pathologies. 

Professor Spinelli carries out a constant research on minimally invasive surgeries, including the single-port surgery, mini-laparoscopy, low-impact surgery and trans-anal techniques (TATME, TAMIS, TTSS). Furthermore, the advanced postoperative recovering is another area of his interest.

He graduated as MD in 2001 at University of Milano. During his education, he won several scholarships: he trained ad University of Berlin Charitè for two years at the Department of General, Visceral and Transplantation Surgery. Also, he obtained his PhD on Surgical Phsyiopathology with a dissertation on enhanced recovery for laparoscopic colorectal surgery in 2011. 

Current Teaching Activity: he is Full Professor of Surgery at Humanitas University. 

Also, Professor Spinelli is general Secretary of the European Society of Coloproctology (ESCP) and Board Member of the Guidelines Committee (GulCom) of the European Crohn Disease and Colitis Organization (ECCO). He is Fellow of the American Society of Colon and Rectal Surgery (FASCRS), Honorary Fellow of the Czech Society of Surgery (CSS) and Honorary Member of the Brazilian College of Digestive Surgery (CBCD). 

He is a member of the International Organization for the study of Inflammatory Bowel Disease (IOIBD) and several other national and international scientific societies. 

In addition, Professor Spinelli serves as Associate Editor for Colorectal Disease (Journal of the Association of Coloproctology of Great Britain & Ireland, Royal College of Surgeons of England, of the European Society of Coloproctology and of the Spanish Society of Coloproctology – Asociación Española de Coloproctología), Diseases of the Colon and Rectum (official journal of the American Society of Colon and Rectal Surgeons), Journal of the Anus, Rectum and Colon (official journal of the Japan Society of Coloproctology).

He is Editorial Board Member of the Journal of Crohn’s Colitis (official journal of the European Crohn’s Colitis Organization), Advisory Board of Coloproctology (official journal of the German Society for Coloproctology – Deutsche Gesellschaft für Koloproktologie) and Editorial Board Member of Updates in Surgery (official journal of the Italian Society of Surgery – Società Italiana di Chirurgia).

Dr. Federico Pessina is the Cranial Neurosurgey Unit Director.

Medical areas of interest: Brain tumors, glioblastomas, low grade gliomas, brain metastases, meningiomas, neuromas, cavernous angiomas, brain aneurysms

Surgical treatment with brain mapping techniques, awake and minimally invasive surgery of all central nervous system tumors.

Surgical treatment of highly complex tumors of the skull base and cranio-cervical hinge: meningiomas, neuromas, craniopharyngiomas, brain stem tumors.

All the tumor pathologies described above are addressed after multidisciplinary multi-specialist evaluation.

The surgical approach is customized to the patient and to the type of lesion, making use of the most advanced intraoperative techniques for malignant brain tumors (neuronavigation, intraoperative neurophysiology, intraoperative CT) and more complex approaches (anterior, posterior and combined petroosectomies, minimally invasive accesses) for benign diseases of the skull base such as meningiomas and neuromas.

Research areas of interest: Experimental protocols in the treatment of glioblastomas

- Prospective protocols in the treatment of brain metastases

- Role of surgical removal and integrated treatments in glioblastomas and malignant brain tumors

- Intracranial meningiomas

- Cadaver lab dissection

Author of more than 60 scientific publications and 5 book chapters, he is member of Italian Society of Neurosurgery (SINCH).

In 2018 he joined the Scientific Committee of European Society of Neuroncology (EANO) and the Skull Base Surgery Committee of World Federation of Neurosurgical Society (WFNS).

Specialized training: 

Prof. Pessina obtained his Degree in Medicine and Surgery in University of  Insubria,  Varese, where he also completed his Residency Program.

From 2007 to 2008 he covered the role of Clinical Fellow in Neurosurgery in Lausanne University Hospital, focusing on image-guided intrinsic brain tumors resection and vascular neurosurgery

In 2018 he covered the Skull Base fellow position in Lariboisiere Hospital, Paris, fully dedicating to skull base surgery and hands-on dissection practice and teaching.

Since 2022, he is Full Professor in Neurosurgery (MED/27) in Humanitas University

Additional information of interest:

Member of the Scientific Committee of the European Association of Neuroncology (EANO)

Publications:  https://www.ncbi.nlm.nih.gov/pubmed/?term=Pessina+Federico

Dr. Daniela Pini is the Head of the Cardio-respiratory rehabilitation Unit.

Medical areas of interest: Dr. Daniela Pini has been working and researching heart failure and has gained considerable experience in the management of advanced forms of this pathology. She is also very interested in the evaluation and "overall" management of patients suffering from this disease, which mainly affects elderly people and who already have other chronic diseases, which, if neglected, can easily impair the effectiveness of treatment for heart failure itself.

Research areas of interest: new therapies for advanced heart failure: replacement therapy of the heart with mechanical assistance devices to the circulation or heart transplant. New drugs and devices. Multidisciplinary patient management programs.

Further information of interest: thanks to the high competence of cardiosurgeons, electrophysiologists and hemodynamists, Humanitas can count, as a clinical cardiologist, on a team that allows it to offer the patient all the range of therapeutic options for heart failure.

From June 2000 to October 2001 she was Visiting Assistant Professor at the Cardiovascular Division Hospital of the University of Pennsylvania. During this period, she worked in the Heart Failure/Heart Transplantation Program, where she participated in the management of patients with advanced heart failure waiting for transplantation, dealing in particular with medical complications in patients with mechanical assistance devices. She has also worked with kidney, kidney-pancreas, pancreas-insulae, lung, liver and heart transplant teams, dealing with the multiple aspects of managing solid organ transplant recipients.

She worked in the Niguarda Ca' Granda Hospital, at the Cardiomyopathy and Heart Transplantation Service, dealing mainly with patients with advanced heart failure and undergoing a cardiac transplant.

Dr. Pini is a member of the coordination committee of the Decompensation Area of the National Association of Medical Hospital Cardiologists – ANMCO. In the last two years she has been mainly concerned on building a network of “heart failure clinics” on the national territory.

Dr. Corrado Lodigiani has been assistant at the Thrombosis Centre of Humanitas research Hospital from 1998 to 2013 and he became Unit Director in 2013. 

Humanitas Thrombosis Center is a state-of-the-art service for the proper management of the diagnosis and therapy of venous thromboembolic pathology (deep and superficial venous thrombosis, pulmonary thromboembolism, visceral venous thrombosis) and arterial (myocardial infarction, cerebral stroke, peripheral arterial disease). 
Other also rare diseases treated are atypical thrombosis, such as the vascular circulation of the retina, the hearing system and the placental circulation during pregnancy. 

Dr. Lodigiani adopts the multidisciplinary approach and works in collaboration with all medical and surgical specialties. In particular, he carries out clinical and instrumental diagnostics (vascular ecocolordoppler) and research on the causes, diagnosis and therapy of thrombotic and bleeding disorders, congenital and acquired. His clinical activity also involves the diagnosis and management of patients suffering from bleeding diseases, such as haemophilia, von Willebrand’s disease and platelet diseases.

Medical areas of interest:  

In recent years, he has devoted himself with particular interest to the testing, in the role of Principal Investigator in International Clinical Studies, of new antithrombotic drugs and, above all, anticoagulants, which are about to be marketed and will constitute a valid and safe alternative to traditional oral anticoagulant therapy (DOACs). He is also working, with great interest, on researching the causes of idiopathic in and the usefulness and effectiveness of some therapeutic strategies, such as the use of anticoagulant drugs, improving the results of artificial insemination procedures. He is the author of numerous articles in international scientific journals and speaker at numerous national and international conferences.

Prof. Andrea Lania has graduated at the Università degli Studi of Milan and is specialized in endocrinology. He is the Unit Director of Endocrinology and Diabetology in Humanitas Research Hospital and his specialization is pituitary diseases, pituitary adenomas, thyroid cancer, pancreatic neuroendocrine tumors, poorly differentiated neuroendocrine carcinomas.

Medical areas of interest:
Pituitary tumors, hypopituitarism, acromegaly, Cushing’s disease and syndrome, neuroendocrine tumors, thyroid and thyroid diseases, adrenal and adrenal diseases, hypogonadism.

Research areas of interest:
Study of the pathogenetic mechanisms of pituitary and neuroendocrine tumors, of the molecular mechanisms responsible for the different response of pituitary and neuroendocrine tumors to medical therapy.

Prof. Lania published 198 peer-reviewed papers (Google Scholar H-Index 47; Scopus H-Index 38, cit tot 4604)

Prof. Lania has a long standing expertise in the field of intra-cellular signaling in endocrine tumors. In particular, in the past ten years, he contributed to analyze the role of PKA regulatory subunits in the pathogenesis and control of cell proliferation of endocrine tumors. Moreover, he contributed to define the role of SSTR5 domains involved in the intracellular trafficking of this receptor in human pituitary cells and to analyze the impact of DR2R and SSTR2&5 polymorphic variants on both the clinical outcome and response to medical treatment in patients with pituitary tumors.

Recently, he contributed to identify the role of cytoskeleton protein FLNA in mediating both intracellular signaling and membrane targeting of somatostatin type 2 receptor and D2R in pituitary and pancreatic neuroendocrine tumors. Finally, he contributed to explore the intracellular mechanisms possibly involved in mediating the interplay between drugs commonly used in the treatment of neuroendocrine tumors.

Previous experience:
2005-2008 Fondazione Ospedale Maggiore Policlinico IRCCS, Milan, Italy
Director of Endocrinologic Day Hospital and surgery on pituitary disorders. 

Publications: https://www.ncbi.nlm.nih.gov/pubmed?term=lania%20A 

Prof. Alessandro Repici is the Director of the Gastroenterology and Digestive endoscopy Unit in Humanitas Research Hospital. Graduated in Medicine and Surgery in 1990 and the following year he won a scholarship at the Department of Gastroenterology Molinette hospital in Turin, where he began his practice in digestive endoscopy. In 1992, he worked with Prof. Claude Liguory as a fellow at the American Hospital in Paris.

In 1994 he became a specialist in Gastroenterology and Digestive Endoscopy at the University of Messina and worked in the Department of Gastroenterology, Ospedale Maggiore Molinette of Turin.

In the following years, he has been working at the Service of Digestive Endoscopy of Altona Hospital in Hamburg, directed by prof. Hagenmuller, and in the Department of Gastroenterology Molinette Hospital in Turin, directed by prof. Rizzetto. In 1999, he was a Research Fellow at the Center for Oncological and Operative Endoscopy of Wellsley Hospital in Toronto.

He teaches Gastroenterology and Digestive Endoscopy at the School of Specialization in Oncology since 2000, at the University of Turin since 2004 and Endoscopy Diagnostic Techniques and Operations at the School of Specialization in General Surgery I and II of the University of Turin.

The clinical activity and research of Prof. Repici mainly focuses on the development of new endoscopic techniques in the field of diagnosis and therapy, with particular attention to new methods of endoscopic removal of cancerous lesions and early in the palliation of advanced gastrointestinal malignancies.

Prof. Repici is coordinator, principal investigator and co-investigator in more than 50 studies, including phase II and III for FDA and EMA approval of new molecules and new instruments for diagnostic and operational endoscopy. 

Prof. Repici collaborates on research projects in the field of endoscopy with the University of Rotterdam, in Haifa, in New York and with several Italian centers. He is a member of various national and international scientific society of Gastroenterology and Digestive Endoscopy.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=repici+alessandro

Dr. Giuseppe Marinari is a specialist in general surgery (1991) and nutrition (1995). He started his career in Bariatric Surgery in 1987 and, since then, he has performed over 7000 bariatric procedures, mainly Sleeve Gastrectomy, Gastric Bypass, and Biliopancreatic Diversion. Dr. Giuseppe Marinari has international experience, and he is one of the leading Bariatric surgeons in Italy. Over the past 10 years, he has focused on the implementation of a high-volume centre (>1250 procedures in 2019). Since 2016, he adopted an Enhanced Recovery After Bariatric Surgery (ERABS) protocol, to improve benefits for the patient. In essence, this means a faster recovery and an early return to daily activities, with a very high patient approval rating.

Obesity is a complex condition that encompasses a variety of comorbidities. Therefore, the role of a bariatric surgeon is multidisciplinary, including the understanding (and sometimes treating) of comorbidities as well as performing surgery.

Bariatrics interested Dr. Giuseppe Marinari at first because it was a new and growing field. He then developed an appreciation for the multidisciplinary aspect. Now Dr. Giuseppe Marinari is eager to help people transform their lives.

Dr. Giuseppe Marinari  was mentored by Prof. N. Scopinaro at the University Hospital in Genoa, Italy. He invented the biliopancreatic diversion (with or without duodenal switch), a malabsorptive bariatric operation. Dr. Marinari is now Director of the Bariatric Center. He has international experience and is one of the leading surgeons in his field. He performs both restrictive and malabsorbative bariatric procedures, mainly using the laparoscopic approach. In Humanitas Reasearch Hospital patients are treated by a multi-disciplinary team. The patients are given full attention and support throughout all the steps along the treatment.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=marinari+giuseppe

Prof. Marco Klinger is director of the School of Specialization in Plastic, Reconstructive and Aesthetic Surgery at the University of Milan and Head of the Operating Unit in Plastic, Reconstructive and Aesthetic Surgery at Humanitas Research Hospital.

He specializes in plastic and reconstructive surgery: treatment of scars, burns, outcomes of bariatric surgery, regenerative medicine and surgery, post-oncological breast reconstruction, breast malformations and skin oncology. Aesthetic plastic surgery: augmentation mammoplasty, mastopexy, reduction mammoplasty, rhinoplasty/ rhinoseptoplasty, lifting, liposuction, abdominoplasty, blepharoplasty and otoplasty.

Research interests: Regenerative medicine and surgery.

Prof. Klinger and his team have performed more than 35,000 plastic surgery and reconstructive surgery; he is the author of over 200 scientific articles, published in national and international journals. Among his most recent and significant studies, the use of lipofilling in treatment of severe burn outcome, scleroderma and chronic pain syndromes, such as Post Mastectomy Pain Syndrome.

Scientific publications: 

http://www.ncbi.nlm.nih.gov/pubmed?term=klinger%20marco

Dr. Bernhard Reimers – Clinical and Invasive Cardiology Unit Director in Humanitas Research Hospital, was born in Germany. He graduated in medicine and surgery in University of Padua (Italy) in 1990, followed by specialization in Cardiology. During the first 3 years of specialization in Cardiology in the Coronary Unit of Padua University, his particular interests were in managing cardiovascular urgency and critical patients, including management of fans, balloon pump, hemofiltration, temporary pacing, placement of central venous pathways and Swan-Ganz catheter. He spent his last year of specialization at the Hemodynamics of Casa di Cura Columbus (Milan), where he acquired his knowledge on the main diagnostic techniques he uses. After a short period of study at the Thoraxcenter of Rotterdam, during which he wrote his first scientific publications, Dr. Reimers has dedicated himself to hemodynamics and cardiovascular surgeries, working as Unit Director main assistant, executing angioplasty, coronary and peripheral procedures, reaching complete autonomy in coronary stenting, atherectomy, ultrasound intravascular and intracoronary doppler.

Since September 1997 he has managed and developed the diagnostic and interventional cardiovascular program at the Department of Cardiology of Mirano (Venice), where, thanks to his achievements, since 2000 the highest number of coronary angioplasties were performed. In 2006 the Unit has performed 975 coronary angioplasties (including 125 primary), more than 400 carotid angioplasty and peripherals. Dr. Reimers became Unit Director and has trained and taught a young team of interventional cardiologists, including 4 completely independent in the performance of coronary angioplasty, which manages both hemodynamics and largely the CCU in close collaboration between the two services. After this important experience, he was invited to be part of Humanitas Research Hospital as Clinical and Invasive Cardiology Unit Director.

Dr. Reimers participates in many scientific studies on the treatment of myocardial infarction considering new interventional or pharmaceutical approaches for primary angioplasty. He was also member of the Technical Commission of the Regional Bid for the purchase of stents. Thanks to Dr. Reimers’ efforts, Hemodynamics of Mirano (Venice) is considered reference center for primary angioplasty and elective complex procedures. Dr. Reimers is considered to be one of the leading experts of carotid angioplasty worldwide. He is preparing a program for interventional treatment of acute stroke. He performs routine renal angioplasty and implants percutaneous devices and endoprosthesis systems for aortic aneurysms.

Dr. Reimers has published, as author or co-author, 77 articles quoted in Medline. The impact factor calculated based on 2006 is 263. He published 9 book chapters and several abstracts for important international conferences dedicated to Cardiology, such as TCT, PCR, National GISE ANMCO, JIM and ESC, were he also performed live invasive procedures.

Dr. Reimers has always considered participation in clinical trials and scientific international events among the main activities of his professional carrier. Besides teaching at University of Tor Vergata in Rome, he organizes many conferences, national and international medical follow-up courses. For over 9 years he has been organizing theoretical and practical courses with lectures and transmission of live procedures in Venice. He has so far organized two editions of TOBI, international meeting dedicated to invasive treatment of total coronary occlusions and bifurcations, three editions of ETI, international conference and the largest in Italy, dedicated to invasive cardiology devices. 

Dr. Reimers was member of the scientific committee in the editions of 2006 and 2007 of National Convention GISE (Italian Group of Hemodynamic Study) and participated at important events dedicated to CAPTURE study, ESIRIUS, SYNTAX, TIMI 38, FINESSE and many others.

Publications: ttp://www.ncbi.nlm.nih.gov/pubmed/?term=bernhard

The prof. Giuseppe Speziale holds the positions of the National Coordinator of Cardiac Surgery of GVM Care & Research, the Director of the Department of Cardiac Surgery at Anthea Hospital and Città di Lecce Hospital, and Director of the Department of Cardiac Surgery of the Santa Maria Hospital. He works at the Cardiological Clinical Institute (ICC) and San Carlo di Nancy Hospital in Rome. Since 2011 he has also held the position of Vice President of GVM Care & Research. In 2012 he occupied the charge of President of Confindustria Puglia, Health Section, and since 2018 he is Vice President of Aiop Puglia (Italian association of private hospitals). The prof. Speziale is a cardiac surgeon specializing in the minimally invasive surgical treatment of valve diseases, expert in minimally invasive repair of the mitral valve, in On and Off Pump myocardial revascularization, in thoracic aortic surgery. He is Co - Founder and President of the Scientific Committee of Mitral Academy, an independent association born from the passion for mitral surgery and the desire to pursue and share excellence in restorative surgery, with particular attention to minimally invasive techniques and the evaluation of potential therapeutic treatments deriving from the use of new technologies. Until 2016 he was elected Director of the Italian Society of Cardiac Surgery. He is part of the following associations: AATS (American Association for Thoracic Surgery), Italian Society of Cardiology Accredited Hospital, SICOA (active member), ISMICS (International Society for Minimally Invasive Cardiothoracic Surgery). Since 2004 he has held the position of Scientific Director of the Italian Cardiopathic Association onlus.

In the field of scientific research, he focuses on new approaches, applicable in the field of minimally invasive and non-invasive mitral, aortic, cardiac arrhythmias and tricuspid surgery. He was the coordinator and researcher of the various projects of the National Research Council on Myocardial Infarction, on the treatment of pulmonary hypertension, on new technologies for carrying out coronary, cardiopulmonary and normothermic bypass. He was an adjunct professor at the Sapienza University of Rome where he held the Chair of Cardiology II, and at the University of Ferrara, where he teaches Cardiac Surgery. He has presented numerous scientific papers at national and international congresses of cardiology and cardiac surgery.

Bibliography: He is co-author of 6 books known nationally and internationally. The most recent one is Advances in Treatments for Aortic Valve and Root Diseases, publisher Springer International Publishing, 2018.

He is Reviewer and author of over 90 publications of multiple journals, such as Seminars in Thoracic and Cardiovascular Surgery, Journal of Geriatric Cardiology, Heart & Lung: The Journal of Cardiopulmonary and Acute Care, European Journal of Cardiothoracic Surgery, The Journal of Thoracic and Cardiovascular Surgery, Journal on Cardiac, Vascular and Thoracic Surgery etc.

Awards: “Top Doctors Awards”, 2021

Dr. Antonello Ceddia specializes in Neurosurgery.

He graduated in Medicine and Surgery at the Catholic University of the Sacred Heart of Rome where, in 1989, he also obtained a specialization in Neurosurgery. After specialization he is a researcher at the Institute of Neurosurgery of the La Sapienza University of Rome and the Institute of Neurosurgery of the Catholic University.

He deals in particular with the treatment of brain tumors and trigeminal neuralgia.

His training, mainly oriented towards Pediatric Neurosurgery and Neuro-Orthopaedics, was completed with attendance at important centers and clinics in the United States and Germany, and with participation in experimental programs and international courses.

After having worked as a Neurosurgeon Assistant in the Neurosurgery Division of the Casa Sollievo Sofferenza Hospital in San Giovanni Rotondo, since 2005 he has held the position of Head of the Neurosurgery Unit in Bari.

Dr. Ferrando is a Surgeon (MD), Doctor of Biomedical Sciences and Oncology (Ph.D) and Specialized in Plastic, Reconstructive and Aesthetic Surgery.

After obtaining the European Scientific Diploma at the European School of Karlsruhe in Germany, Dr. Ferrando attended the Faculty of Medicine and Surgery of the University of Turin, where he graduated with full marks and with dignity of publication in 2004. 

During his specialist school in Plastic, Reconstructive and Aesthetic Surgery he carried out numerous fellowships abroad, including one focused on reconstruction for infantile facial malformations at Great Ormond Street Hospital in London, England, with Dr. Sommerlad; on microsurgical breast reconstruction at St. Andrew's Center for Plastic Surgery and Burns in Chelmsford, England, with Dr. Ramakrishnan; and breast reconstruction with acellular dermal matrices at Georgetown University Hospital, Washington D.C., USA, with Dr. Spear.

Returning to Italy in 2011, Dr. Ferrando specialized with honors in Plastic, Reconstructive and Aesthetic Surgery at the University of Turin and, again at the same University, in 2017 he completed his doctorate in biomedical sciences and oncology. Subsequently, Dr. Ferrando completed the first level Master's degree in breast surgery at the University of Ancona and is currently attending the second level master's degree in breast oncoplasty at the University of Genoa.

Currently, Dr. Ferrando works for few clinics in Turin as 2nd level Medical Director at the Plastic and Reconstructive Surgery department of the C.T.O. Hospital of Turin, directed by Doctor Malan, where he mainly deals with breast surgery, skin tumors and traumas and at the Clinica Santa Caterina da Siena at the Reconstructive and Plastic Surgery department.

He is a member of the Italian Society of Plastic, Reconstructive and Aesthetic Surgery (S.I.C.P.R.E.), of the Italian National Association of Breast Surgeons (A.N.I.S.C.), of the Italian Society of Hospital Surgeons (S.I.C.O.) and of the European Society of Oncological Surgery (E.S.S.O.)

In addition to following students of the Medicine and Surgery course of the University of Turin for the Degree Thesis in his field of specialty, he is regularly invited as a speaker at national and international courses and congresses. His main research areas are: acellular dermal matrices and negative pressure therapy on closed surgical wounds. 

Currently, Dr. Ferrando has published 11 original articles in national and international scientific journals, 21 abstracts for national and international congresses and has been awarded the prize: "best European article of 2019" by the international journal Plastic and Reconstructive Surgery Global Open.

In clinical practice he carries out all breast surgery operations, both reconstructive and oncological, those for the removal of skin tumors and for the reconstruction of congenital malformations and traumas, in addition to Aesthetic Surgery operations and the most advanced Aesthetic Medicine procedures.

Pediatric Neurologist

Leading expert in neurorehabilitation

The Director of Doctor’s Equipe Clinic. The inventor of the Microfat system. Maxillofacial Surgery and Aesthetic Cosmetic Correction specialist.

Surgeon, senologist

Oncologist-urologist

Dr. Giuseppe Curigliano is the head of the Division of Early Drug Development at the European Institute of Oncology and an Associate Professor of Medical Oncology at the University of Milano in Italy. He is the founding member and scientific chair for the International Cardio-Oncology Society (ICOS) and has received the first ESO Umberto Veronesi Award in Vienna in 2017 and the Fellowship of the European Academy of Cancer Sciences in Paris in 2017.