Best CyberKnife for brain tumor pediatric neurosurgeons in Istanbul: TOP 12 doctors

Mustafa Solak, M.D. is a medical doctor who graduated from Hacettepe University School of Medicine and has completed residencies at Istanbul Sisli Etfal Teaching and Research Hospital and a fellowship at Hacettepe University Cancer Institute. He specializes in Breast Cancer, Testicular Cancer, Ovarian Cancer, Lung Cancer, Head-Neck Cancer, and Gastrointestinal Cancers. He has also worked at the University of Texas MD Anderson Cancer Center, Hitit University Corum Training Hospital, and Medical Park Hospital.

Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011 

H index: 10, I10 Index: 12 Citations: 296

 Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery. 

Work & Training experience:

2004-2011: Gazi University, Department of Neurosurgery (Residency)

 2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland 

2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland 

2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon

 2012 – 2013: Cankiri State Hospital, Neurosurgeon 

2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof) 

2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands 

2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon

 2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center) 

2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.) 

Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses. 

Clinical areas of interest:

 • Stereotactic & Functional Neurosurgery

 • Surgery for movement disorders

• * MR Guided Focused Ultrasound (MRgFUS)

 • Gamma Knife Radiosurgery 

• Surgery for pain & spasticity 

• Psychosurgery

Research areas of interest: 

• Deep brain stimulation

• * MR Guided Focused Ultrasound (MRgFUS)

 • Stereotactic radiosurgery 

Administrative duties:

 • Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017 

• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019

 • Turkish Skull Base Society: Board member 2016-2018

 • Turkish Skull Base Society: Supervisory board member 2018-2020

 • Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still 

Memberships: 

• WSSFN (World Stereotactic & Functional Neurosurgery Society) 

• ESSFN (European Stereotactic & Functional Neurosurgery Society)

 • Deep Brain Stimulation and Movement Disorders Surgery Society

 • Deep Brain Stimulation Society 

• International Stereotactic Radiosurgery Society 

• Leksell Gamma Knife Society 

• EANS (European Association of Neurosurgical Societies) 

• Turkish Neurosurgical Society

• Turkish Skull Base Society

Sample Publications: 

1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001 

2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529. 

3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716. 

4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741. 

5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942. 

6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759. 

7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232. 

8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430. 

9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533. 

10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560. 

11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559. 

12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279. 

13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921. 

14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994. 

15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102. 

16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698. 

17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507. 

18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852. 

19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.

Education and Career

2011 – 2015, (Internal Medicine Specialist) Istanbul University Istanbul School of Education and Career

Medicine Department of Internal Medicine

2015 – 2016, (Internal Medicine) Specialist Istanbul Haydarpasa Numune Training and Research Hospital

2016 – 2019, (Medical Oncology) Istanbul University Istanbul School of Medicine Department of Medical Oncology

2019 – 2021, (Medical Oncology Specialist) - Istanbul Haydarpasa Numune Training and Research Hospital

2021 – 2024, (Associate Professor) Marmara University School of Medicine Department of Medical Oncology

Memberships in Scientific Organizations

ASCO

ESMO

TTOD 

AVOD 

Publications

In the field of oncology, he has published over 30 peer-reviewed articles at both international and national levels.

Awards Received

EAACI The European Academy of Allergy and Clinical Immunology 2019 Best Poster Award

"The top 3rd verbal presentation, IGICC (11th International Gastrointestinal Cancers Conference – IGICC2021)"

Speeches Delivered at National Congresses, Conferences, and Symposia:

Courses, Meetings, and Certificates

ESMO certified Medical Oncologist since 2019

Certificates

1. The Course of Functional and Stereotactic Neurosurgery, 1990, Oulu, Finland.

2. European Course participation that holds by EANS for 5 years cycle (Amsterdam/1988, Rostock/1989, Çeşme/1994, Klagenfurt/1995, Aalborg/1996).

3. "Primary Examination" for European Board was passed in Klagenfurt,1995, Austria.

4."Advanced Training on Functional Disorders with Leksell Gamma Knife", 2004, Marseille, France.

5. "Advanced Training on Vestibular Schwannomas and Skull Base Surgery wiyh Leksell Gamma Knife", 2004, Marseille, France.

6. The certificate for "DISC Nucleoplasty in Cervical and Lumbar Disc Diseases", 2004, Freiburg, Germany.

7. "Neuropathfinder" Train - the - Trainer Meeting, 2009, Wien, Austria.

8. " Neuropathfinder" Train - the - Trainer Meeting, 2011, Athens, Greece.

9. The certificate for "Full- Endoscopic Spine Surgery", 2011, Herne, Germany.

He was born in Niğde which is the city middle part of Anatolia. He studied high school in Adana. He graduated from Ankara University Medical School of Medicine. He started his career at Bakırköy Neurological Sciences Hospital in Zeki Oral MD.’s Clinic in 1987 and finished his Neurosurgery residency in 1993. During this period, he completed his micro neurosurgery education, which was a breakthrough for him, at Zurich University “Professor M. Gazi Yaşargil’s Clinic”.

Between 1993-2003, he worked as a teaching assistant and then as an assistant professor at the Professor Necmettin Pamir’s Clinic, Faculty of Medicine, Marmara University. At the same time, he obtained clinical and surgical gains in the field of neurooncology and vascular neurosurgery at Professor Donlin M. Long and Daniele Rigamonti's Clinic at Johns Hopkins University, USA. In 2003, he received the title of Associate Professor of Neurosurgery.

Between 2004-2010, he worked as Chief of Clinic in Göztepe Training and Research Hospital of Ministry of Health. During this period, he led his clinic to become the only accredited clinic by EANS (The European Association of Neurosurgical Societies) in Turkey, with its educational and care services. During this period, he completed his endoscopic skull base training starting at the University of Pittsburgh.

In 2010, he started to work for Acıbadem University Faculty of Medicine and became a Professor of Neurosurgery. He established the Neurosurgery Department in Medipol University Faculty of Medicine on 2012. He served as a Head of Neurosurgery Department in Memorial Health Group Istanbul Hospitals between 2014-2018. He served Neurosurgery Department of Maslak Hospital of Acıbadem Health Group with his team between 2018- September 2021.

Since 01.10.2021, He have started to work with his team at my private clinic located in Fulya and Ulus Hospital of Liv Health Group.

He served as the founding chairman of ”Skull Base Society” in Turkey. He is also a member of the Executive Committee of the European Skull Base Society (ESBS).

There are more than 110 scientific papers which he hs published in international refereed journals (SCI/SCIEx) and in national refereed journals and 18 scientific articles. He Has more than 250 scientific congress presentations, published books and chapters in books.