Born in 1957 in Kyiv. Ukrainian.
Since 1978, scientific and practical activity in the field of orthopedic pathology (pathophysiology of scoliosis and scoliotic deformations of the spine and chest, vertebrology). The first scientific publication on vertebrology in 1980.
1980 – graduation from the medical faculty of the Kyiv Medical Institute.
1981 to 1984 Anesthesiologist-resuscitator. Scientific and practical work in the field of treatment of pain syndromes and vegetology, use of stimulation of nerve trunks and reflexogenic zones, acupuncture, manual medicine, non-surgical treatment of scoliosis, physical rehabilitation.
Since 1984 and up to the present moment, he has been professionally engaged exclusively in practical and scientific problems of diseases of the spine and joints, vertebroneurology, neurology, traumatology-orthopedics, rheumatology.
1984 – employee of the laboratory of problems of osteochondrosis of the spinal column of the university research laboratory center* (Academician A.A. Bogomolets National Medical University). Scientific and practical activity in the field of diagnostics, treatment and rehabilitation of pathology of the musculoskeletal system (spine, joints, muscles) and nervous system.
1990 - defense of a candidate's dissertation on neurological disorders in spinal pathology " Early segmental neurological manifestations of osteochondrosis of the thoracic spine " (specialty - neurology)
1994 - defense of a doctoral dissertation on the mechanisms of formation of neurological pathology in spinal pathology (vertebroneurology) “ Mechanisms of formation of vertebral neurological pathology in the case of functional blockage of the spinal rox segments ” (2 specialties: neurology and traumatology-orthopedics)
Since 1995 – Professor of the Department of Neurology and Rehabilitation Medicine of the National Medical University named after Academician A.A. Bogomolets.
1995 Founded the first clinic of Vertebroneurology in Ukraine, head of the department of vertebroneurology at the Central City Clinical Hospital of Kiev - the clinical base of the Department of Neurology and Rehabilitation Medicine of the National Medical University.
2004 Established the diagnostic department of the Vertebroneurology Clinic.
2011 Established the Ukrainian Institute of Musculoskeletal Medicine and Neurology based on the Meddiagnostika Center.
Sphere of scientific and practical interests
Science
More than 80 scientific papers , 12 inventions in the field of pathology of the musculoskeletal system and nervous system.
Key research:
Dr. Yaroslav Miroshnykov is a highly experienced and qualified urologist, andrologist, sex therapist, and director of the Renaissance Technology clinic Medical Center with 22 years of medical experience and education. He has received numerous accolades and honors, and has extensive experience in a variety of medical fields.
Read moreDr. Yunus Keser YILMAZ is a Cardiovascular Surgeon Specialist and Complementary and Integrative Medicine Physician with extensive experience and expertise in the fields of Cardiovascular Surgery and Complementary and Integrative Medicine.
Read moreDr. Borghesi leads the Neurosurgery Unit at Maria Cecilia Hospital, where his team performs around 1,000 advanced neurosurgical procedures annually. His approach combines years of experience with the latest technological innovations to ensure patients receive the most effective treatments available. Specializing in spinal surgeries (including cervical, dorsal, and lumbar procedures), Dr. Borghesi utilizes both posterior and anterior techniques to help patients regain mobility and relieve pain. Throughout his career, he has successfully performed over 4,500 complex surgeries, offering life-changing solutions for patients with challenging cranial and spinal conditions.
For brain tumor removal, he and his team employ advanced video-micro-surgical techniques, including the use of a digital microscope with 4K 3D imaging, which allows for enhanced precision and minimal invasiveness. Patients suffering from conditions like trigeminal neuralgia, facial spasms, and tumors of the posterior cranial fossa can benefit from Dr. Borghesi’s expertise in minimally invasive surgery, having treated over 400 cases with innovative techniques.
Dr. Borghesi has trained in various top-tier international hospitals, learning from the best to provide high-quality care to his patients:
He is the author of numerous scientific publications in national and international journals and volumes. In 1997 he was consultant of the "Medical Review" Journal.
Read moreDr. Motti works at the Neurosurgery Department at Maria Cecilia Hospital, as the coordinator of the Gamma Knife Operating Unit, and neurosurgeon in charge of the Stereotaxic Neurosurgery Unit, one of the few centers in Italy, which specializes in the Gamma Knife treatments.
He is an active member of several research companies focused on Gamma Knife: Italian Society of Neurosurgery, Rome; Gamma Knife Society, Stockholm; European Gamma Knife Society, Madrid. In 1982 he obtained the patent for interfacing the Talairach stereotaxic helmet with computerized axial tomography methods. In 1987 he made the first brain implantation of rgic cells in Parkinson's disease in Italy. He is responsible for training courses at national and international levels, such as courses in Stereotaxic Techniques, Functional Neurosurgery, Radiosurgery at the School of Specialization in Neurosurgery, by the University of Milan; He was an Invited speaker at the "Compliance in radiosurgery" course at the GKSociety meeting in Seoul, South Korea; Organizer of the First European Meeting of Gamma Knife Users, in 1996 in Milan and its subsequent editions.
He is often invited as an instructor in the first weeks of the opening of the new Gamma Knife centers, such as from the Hospital of the University of California Davis, Sacramento, California; or the Arsenji Hospital in Bucharest, Romania etc.
Author and co-author of about 100 publications and contributors to national and international journals. In the seventies he contributed as Assistant Editor to the editorial board of the Journal of Neurosurgical Sciences. For twenty years he was a Consultant in medical libraries as an expert in research techniques and bibliographic archives.
Read moreAssoc. Prof. Nesrin Helvacı Yılmaz graduated from Hacettepe University in 2000 as a Medical Doctor. She completed her specialty training in the Department of Neurology at Ankara University in 2006.
She started her compulsory service in Mardin Nusaybin State Hospital in 2007. Nesrin Helvacı Yılmaz continued her duty in Gaziantep 27 December State Hospital in 2008. She worked as a neurologist at Biophysis Nilüfer Medical Center and Ali Osman Sönmez Oncology Hospital in Bursa between 2010-2011, and at Istanbul Universal Aksaray Hospital between 2011-2012. From October 2012, she started to work as a Doctor Lecturer in Istanbul Medipol University Neurology Department. Nesrin Helvacı Yılmaz received the title of associate professor in 2021. In 2015, she worked as an Honorary Observer in Parkinson's Disease and Deep Brain Stimulation (Neuromodulation) at UCL Queen Square Institute of Neurology, National Hospital for Neurology in London. She took part in many training programs on Deep Brain Stimulation (Neuromodulation) in Turkey and abroad between 2013-2022.
Regarding her speciality in Parkinson's disease and movement disorders, she has 5 Tubitak projects, a 2-chapter book , 30 clinical researches and 80 reports presented in domestic and abroad. Assoc. Prof. Nesrin Helvacı Yılmaz, who is still working within the staff of Medipol University, managed the Parkinson's and Movement Disorders Unit of the Department of Neurology during her working time and plans Deep Brain Stimulation therapy applications with the neurosurgical team.
Since September 2018, she has been working as a coordinator for student education in the 5th semester of Neurology. As of December 2022, she has developed treatment plans for patients at Medipol University Istanbul Parkinson's Disease and Movement Disorders Center (PARMER) and provides the most appropriate personal medical follow-up and treatment support for each patient.
PUBLICATIONS
1-Yilmaz N, Yigit A, Akbostanci MC. Clozapine induced epilepsy. Revue Neurologique 2004, Nov;160/11:1093.
2-Nesrin Helvacı Yılmaz, Nursel Aydın. Sıcak Su Epilepsili Bir Olgu. Türkiye Klinikleri Nöroloji Dergisi 2004/Cilt2/Sayı 2.
3-Nesrin Helvacı Yılmaz, Nursel Aydın. Refleks Epilepsiler. Türkiye Klinikleri Nöroloji Dergisi 2004/Cilt2/Sayı 2.
4-Mine Hayriye Sorgun, Bilge Koçer, Funda Kaplan, Nesrin Yılmaz, Nezih Yücemen, Canan Yücesan. Multipl Sklerozda Kraniyal Nöropati. Turk Norol Derg 2011;17:137-142.
5-Nesrin Helvacı Yılmaz, Gökçen Duymaz, Mehmet Akif Yaşar. Parkinson Hastalığı Olan Bir Olguda Malign Sendrom. Turk Norol Derg 2012:18;123-125.
6-Yilmaz NH, Akbostanci MC, Oto A, Aykac O. Prevalence of restless legs syndrome in Ankara, Turkey: an analysis of diagnostic criteria and awareness. Acta Neurol Belg 2012 Oct 31. [Epub ahead of print].
7-Yılmaz NH, Bingol AP. Sensitivity and specificity of Ankara University Cerebral Dominance Inventory in comparison with the Wada test. Acta Neurol Belg 2013 Jun 6 [Epub ahead of print].
8-Sema Demirci, Nesrin Helvacı Yılmaz, Efsun Şenocak, Fatih Han Bölükbaşı. Pons Kavernomu: Kranial Manyetik Rezonans Görüntüleme Bulguları. Turk Norol Derg 2012:19:72.
9-Nesrin Helvacı Yılmaz, Sinem Atik Güngör, Taflan Sahlepçi. Küçük hücreli akciğer kanseri tedavisinde cisplatin kullanımı sırasında gelişen akut iskemik inme: olgu sunumu. J Kartal TR. Baskıdaki Makaleler: KEAH-26937.
POSTERLER:
-Serebral venöz tromboz ve bruselloz Birlikteliği; Olgu Sunumu (42. Ulusal Nöroloji Kongresi-Antalya 2006)
-Waldenström makroglobulinemisine eşlik eden epileptik nöbetler ve nonkonvülsif status epileptikus (42. Ulusal Nöroloji Kongresi-Antalya 2006)
-Prevalence of Restless Legs Syndrome in Ankara, Turkey (16. Uluslararası Parkinson ve Hareket Bozuklukları Kongresi-Dublin 2012).
-Konjenital Miyastenik Sendrom (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).
-Beşinci haftada duyusal iletimleri normal olan bir enjeksiyon nöropatisi olgusu (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).
-Olgu sunumu: Mononöritis mültipleks ve lepra (29. Ulusal Nörofizyoloji EEG-EMG Kongresi- Antalya 2013).
-İdyopatik Parkinson Hastalığı’nda hızlanmış unutma ve uyku kalitesi (10. Ulusal Parkinson ve Hareket Bozuklukları Kongresi-Antalya 2013).
-Hiperglisemiye bağlı hemikore ve bazal gangliyon hiperintensitesi: Olgu sunumu (10. Ulusal Parkinson ve Hareket Bozuklukları Kongresi-Antalya 2013).
Read moreEDUCATION
EXPERIENCE
ACCOLADES
General Information and Presentation
He completed his primary education at Şenlikköy Primary School and his secondary education at the Istek Foundation Florya Bilge Kagan High School. He graduated from Istanbul University Cerrahpaşa Faculty of Medicine in 2001. He completed his specialist education in Istanbul Medical Faculty Neurology Department in 2006. In 2006 he worked at the Neurology Clinic and the PharmaZentrum Research Center of the Faculty of Medicine of the University of Basel, Switzerland. Between 2007 and 2011, Bakırköy Prof. Dr. He worked at Mazhar Osman Mental Health and Neurological Diseases Training and Research Hospital in the 3rd Neurology Clinic and in the Dementia and Movement Disorders policlinics. Since October 2011, he has been working at Istanbul University of Science, Faculty of Medicine, Neurology, USA.
Experience
İstanbul Bilim University Faculty of Medicine Neurology,
Şişli Florence Nightingale Hospital
Kadıköy Florence Nightingale Hospital Neurology Clinics,
Gayrettepe Metropolitan Florence Nightingale Hospital PET department.
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Neurosurgery Training: Gazi University, Department of Neurosurgery, 2011
H index: 10, I10 Index: 12 Citations: 296
Dr Mehmet Tonge has international and nationwide 32 publications, 12 book chapters, 92 oral and poster presentations and 41 invited lectures, mostly on Stereotactic and Functional Neurosurgery.
Work & Training experience:
2004-2011: Gazi University, Department of Neurosurgery (Residency)
2008: Zurich University Hospital, Department of Neurosurgery (Intraoperative MRI applications), Switzerland
2008: Zurich University Hospital, Department of Neurosurgery: Microneurosurgery, white matter dissection, interventional neuroradiology courses, Switzerland
2011 – 2012: Sinop Ataturk State Hospital, Neurosurgeon
2012 – 2013: Cankiri State Hospital, Neurosurgeon
2013 – 2014: Istanbul Medipol University, Department of Neurosurgery & Gamma Knife Center (Ass Prof)
2013 – now: Maastricht University Neurosurgery & Neuroscience Department (Visiting scientist, PhDc) The Netherlands
2014: Maastricht University, The Netherlands: Deep Brain Stimulation Fellowship 2014-2018: Istanbul Memorial Hospital Neurosurgery: Staff Neurosurgeon
2016-2018: Istanbul Florence Nightingale Hospital (Consultant, Gamma Knife Center)
2018-now: Istanbul Medipol University (Stereotactic & Functional Neurosurgery, Gamma Knife Center) Ass. Prof.)
Dr Mehmet Tonge has completed 4-year cycle EANS (European Association of Neurosurgical Societies) Training courses.
Clinical areas of interest:
• Stereotactic & Functional Neurosurgery
• Surgery for movement disorders
• Gamma Knife Radiosurgery
• Surgery for pain & spasticity
• Psychosurgery
Research areas of interest:
• Deep brain stimulation
• Stereotactic radiosurgery
Administrative duties:
• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member 2015- 2017
• Turkish Neurosurgical Society, Sterotactic & Functional Neurosurgery Section: Board member (Secretary) 2017-2019
• Turkish Skull Base Society: Board member 2016-2018
• Turkish Skull Base Society: Supervisory board member 2018-2020
• Deep Brain Stimulation and Movement Disorders Surgery Society: Executive Board Member, (Accountant) 2023-still
Memberships:
• WSSFN (World Stereotactic & Functional Neurosurgery Society)
• ESSFN (European Stereotactic & Functional Neurosurgery Society)
• Deep Brain Stimulation and Movement Disorders Surgery Society
• Deep Brain Stimulation Society
• International Stereotactic Radiosurgery Society
• Leksell Gamma Knife Society
• EANS (European Association of Neurosurgical Societies)
• Turkish Neurosurgical Society
• Turkish Skull Base Society
Sample Publications:
1. Tonge M. Technological developments in electric based DBS. Deep Brain Stimulation 2024 4(36-41) DOI: https://doi.org/10.1016/j.jdbs.2023.12.001
2. Akgul E, Onan HB, Islek I, Tonge M, Durmus Y, Barburoglu M, Azizova A, Erol C, Hakyemez B, Sencer S, Aydin K, Arat A. Flow diverter stents in the treatment of recanalized intracranial aneurysms. Interv Neuroradiol. 2021 Aug;27(4):481-489. doi: 10.1177/1591019921990507. Epub 2021 Jan 28. PMID: 33509011; PMCID: PMC8580529.
3. Mulders AEP, Temel Y, Tonge M, Schaper FLWVJ, van Kranen-Mastenbroek V,Ackermans L, Kubben P, Janssen MLF, Duits A. The association between surgical characteristics and cognitive decline following deep brain stimulation of the subthalamic nucleus in Parkinson's disease. Clin Neurol Neurosurg. 2021 Jan;200:106341. doi: 10.1016/j.clineuro.2020.106341. Epub 2020 Nov 3. PMID: 33160716.
4. Wetzelaer P, Vlis T, Tonge M, Ackermans L, Kubben P, Evers S, Kocabicak E, Temel Y. Management of Hardware Related Infections after DBS Surgery: A Cost Analysis. Turk Neurosurg. 2018;28(6):929- 933. doi: 10.5137/1019-5149.JTN.21511-17.1. PMID: 29465741.
5. Bedirli N, Emmez G, Ünal Y, Tönge M, Emmez H. Effects of positive end- expiratory pressure on intracranial pressure during pneumoperitoneum and Trendelenburg position in a porcine mode. Turk J Med Sci. 2017 Nov 13;47(5):1610-1615. doi: 10.3906/sag-1609-17. PMID: 29152942.
6. Sari R, Tonge M, Bolukbasi FH, Onoz M, Baskan O, Silav G, Elmaci I. Management of Failed Cranioplasty. Turk Neurosurg. 2017;27(2):201-207. doi: 10.5137/1019-5149.JTN.15395-15.0. PMID: 27593759.
7. Tonge M, Kocabicak E, Ackermans L, Kuijf M, Temel Y. Final Electrode Position in Subthalamic Nucleus Deep Brain Stimulation Surgery: A Comparison of Indirect and Direct Targeting Methods. Turk Neurosurg. 2016;26(6):900-903. doi: 10.5137/1019-5149.JTN.13739-14.1. PMID: 27337232.
8. Tonge M, Ackermans L, Kocabicak E, van Kranen-Mastenbroek V, Kuijf M, Oosterloo M, Kubben P, Temel Y. A detailed analysis of intracerebral hemorrhages in DBS surgeries. Clin Neurol Neurosurg. 2015 Dec;139:183-7. doi: 10.1016/j.clineuro.2015.10.017. Epub 2015 Oct 23. PMID: 26513430.
9. Silav G, Bölükbaşı FH, Özek E, Tönge M, Önöz M, Elmacı İ. A Simple Technique for Bone Storage after Decompressive Craniectomy in Children. Pediatr Neurosurg. 2015;50(3):161-4. doi: 10.1159/000381748. Epub 2015 May 14. PMID: 25998533.
10. Yilmaz MB, Donmez H, Tonge M, Senol S, Tekiner A. Vertebrojugular arteriovenous fistula and pseudoaneurysm formation due to penetrating vertebral artery injury: case report and review of the literature. Turk Neurosurg. 2015;25(1):141-5. doi: 10.5137/1019-5149.JTN.8247-13.1. PMID: 25640560.
11. Kurt G, Tönge M, Çeltıkçı E, Çapraz I, Serdaroğlu A, Bılır E. Surgery for intractable temporal lobe epilepsy: experience of a single institution. Turk J Med Sci. 2014;44(5):866-70. doi: 10.3906/sag-1307- 30. PMID: 25539559.
12. Yılmaz MB, Tönge M, Emmez H, Kaymaz F, Kaymaz M. Neuroprotective effects of quetiapine on neuronal apoptosis following experimental transient focal cerebral ischemia in rats. J Korean Neurosurg Soc. 2013 Jul;54(1):1-7. doi: 10.3340/jkns.2013.54.1.1. Epub 2013 Jul 31. PMID: 24044072; PMCID: PMC3772279.
13. Yilmaz MB, Egemen E, Tonge M, Kaymaz M. Transoral protrusion of a peritoneal catheter due to gastric perforation 10 years after a ventriculoperitoneal shunting: case report and review of the literature. Turk Neurosurg. 2013;23(2):285-8. doi: 10.5137/1019-5149.JTN.4904-11.1. PMID: 23546921.
14. Omerhodzic I, Tonge M, Matos B, Musabeliu E, Raspanti C, Ferdinandov D, Galimova R, Muroi C, Balik V, Kursumovic A. Neurosurgical training programme in selected European countries: from the young neurosurgeons' point of view. Turk Neurosurg. 2012;22(3):286-93. doi: 10.5137/1019- 5149.JTN.5133-11.0. PMID: 22664994.
15. Ergun E, Kurt G, Tonge M, Aytar H, Tas M, Baykaner K, Ceviker N. Effects of phenytoin sodium on dura mater healing in a rat model of CSF leakage. Turk Neurosurg. 2011;21(4):471-6. PMID: 22194102.
16. Emmez H, Tonge M, Tokgoz N, Durdag E, Gonul I, Cevıker N. Radiological and histopathological comparison of microporous polysaccharide hemospheres and oxidized regenerated cellulose in the rabbit brain: a study of efficacy and safety. Turk Neurosurg. 2010 Oct;20(4):485-91. doi: 10.5137/1019- 5149.JTN.3300-10.2. PMID: 20963698.
17. Emmez H, Yildirim Z, Kale A, Tönge M, Durdağ E, Börcek AO, Uçankuş LN, Doğulu F, Kiliç N, Baykaner MK. Anti-apoptotic and neuroprotective effects of α-lipoic acid on spinal cord ischemiareperfusion injury in rabbits. Acta Neurochir (Wien). 2010 Sep;152(9):1591-600; discussion 1600-1. doi: 10.1007/s00701-010-0703-9. Epub 2010 Jun 10. PMID: 20535507.
18. Kurt G, Tonge M, Börcek AO, Karahacioglu E, Gurel O, Baykaner K, Ceviker N, Aykol S. Fractionated gamma knife radiosurgery for optic nerve tumors: a technical report. Turk Neurosurg. 2010 Apr;20(2):241-6. doi: 10.5137/1019-5149.JTN.1681-09.3. PMID: 20401852.
19. Emmez H, Kale A, Tönge M, Cakir A, Ceviker N. Two meningiomas with different histological grades in the same patient. Case report. Neurol Med Chir (Tokyo). 2010;50(8):686-8. doi: 10.2176/nmc.50.686. PMID: 20805656.
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