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Israel Tel Aviv

KADCYLA for treating HER2+ early breast cancer or HER2+ metastatic breast cancer.

Sourasky Medical Center (Ichilov) Israel Tel Aviv
84% Clients recommended this clinic
4.4
Good score based on 138 patient reviews Read reviews

Clinical oncologist

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Ari Raphael
Oncologist, specialist in medical oncology - lung and breast cancer. Director of oncology day hospitalization, Sourasky Medical Center Tel Aviv, Ichilov Hospital. Senior physician in the lung and breast cancer unit. Researcher in the cancer clinical research unit, molecular clinic. Decoding Genomic Sequencing (NGS). Senior researcher in phase I-II studies including intratumoral injections. Translational research - TCR at Bar-Ilan University and ctDNA at the Institute of Pathology in Ichilov
17 years of experience
About
Dr. Ari Raphael is an expert in oncology and cancer biology with 17 years of experience. He has contributed to clinical research, notably a cross-sectional study aimed at improving oncologic patients' participation in clinical trials. He provides a range of treatments including Chemotherapy, Immunotherapy, Targeted therapy, Radiotherapy, and Hormone therapy.

Before and After Pictures

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Program details

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With a specialization in lung and breast cancer, our esteemed oncologist has high success rates in treating Adenocarcinoma. At our internationally recognized clinic, we offer advanced treatment options, ensuring a 90% average success rate in oncology treatment.
Read about the program benefits
Medical Procedures

  • Immunotherapy
  • Targeted therapy

Duration

  • 1 days in the hospital
  • 1 day in the hotel

Transport

Transfer to the hospital

Additional information

Treatment is carried out in the day hospital of the oncology department

24/7 Bookimed assistance

Personal medical coordinator

Medical travel arrangements — booking of air tickets and hotel rooms at special partner prices

Patient advocacy during medical travel

Program price

$2030

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Patient reviews

4.4
1 star
0%
2 stars
0%
3 stars
0%
4 stars
5%
5 stars
95%
Sourasky Medical Center (Ichilov) overall rate includes
5.0/5
Doctor
4.9/5
staff
4.4/5
Facilities
5.0/5
Language assistance
4.8/5
Support

Татьяна • Breast cancer
Russian Federation

Aug 30, 2018
Verified review.
Verified review.
-I was lucky that I went to the website "Bukimed"
I'll start with the most important thing. The most important thing in a huge sea of ​​information is to choose the right "light", "lighthouse", which will point the way to a person who finds himself in this abyss with a limited time and money limit. I was lucky that I went to the website "Bukimed". I was contacted by coordinating physician Ivan Koval, who was very tactful and at the same time confidently leading me forward. I rushed from one clinic to another, from one operator to another, he calmly explained to me all the pros and cons and was support even when I already completely refused his help and tuned in to another operator. Even then, he very tactfully warned about possible pitfalls and continued to be an assistant. As a result, I took his advice and did not regret it. Hi Medical is very sympathetic to customers, helps with everything, tries to reduce customer costs, where possible. Organizes as quickly as possible consultations and time-examination. Special thanks to Victoria, who spins like a squirrel in a wheel to keep everything in order, always in touch and will not rest until the matter is brought to an end. My treatment is not yet complete, but I'm glad that I got into such a nice team, which brightens up, as much as possible, a person's life one-to-one with his illness. Thank you and for a healthy sense of humor, it also helps to overcome illness!))) And, still. Ivan was in touch with me throughout his stay in Israel. He was convinced that I flew, I was met and I was engaged. He made sure that I get everything that was promised. And after my return home, too, remains in touch, helping in my next steps. Thanks for the help!
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Orislava Chepurenko • Breast cancer
Russian Federation

Jul 24, 2018
Verified review.
Verified review.
To other patients who want to be treated at this clinic, I can say with certainty that thanks to the coordinator of Victoria and her team, they will receive not only qualified medical care, but also warm human relations and help in the organization of treatment
Good afternoon! I am grateful to Konstantin for advising me on this clinic.  For the past 7 months I've been there I'm paying special thanks to the coordinator of Victoria and thanks to the whole team. Victoria is not only the coordinator of my treatment in the clinic, but she has become for me a very close person with whom one can consult, who can "weep in the vest." During the treatment, if necessary, she provided me with transportation, mostly free of charge. I tried to save my money if possible. Organized a convenient for me schedule of visits, consultations of doctors and medical procedures. The clinic has excellent qualified doctors and the latest equipment. To other patients who want to be treated at this clinic, I can say with certainty that thanks to the coordinator of Victoria and her team, they will receive not only qualified medical care, but also warm human relations and help in the organization of treatment.
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Людмила • Sarcoma
Ukraine

Oct 31, 2022
Verified review.
Verified review.
I recommend
The staff is great. At the moment, we are waiting for the results of the tests, since the wrong diagnosis was made in Ukraine. In Ukraine, sarcoma was treated for 7 months and it is gone. We are not saying that there is no oncology, but the fact that there is no sarcoma is already pleasing. Received very nicely and politely. The coordinators are Russian-speaking. Every day they keep track of all matters. Those who passed the tests were not left alone for a single minute. Currently, we are waiting for a meeting with an oncologist and a radiologist. I recommend
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Айнаша • Leiomyosarkoma
Kazakhstan

Dec 6, 2019
Verified review.
Verified review.
In general, I am very pleased with this opportunity
I was advised to do a glass review, at first they turned to Germany and they did not confirm the diagnosis there, but there were doubts about the diagnosis and Israel was the third country, which turned out to be the right decision. I believe that this feature is very useful, since the diagnosis is not comic and you need to deal with the revision of the blocks. Coordinator Anastasia helped, very quickly found the people who transported our glasses, in this regard, many thanks. In general, I am very pleased with this opportunity.
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Заира • Pancreatic cancer
Russian Federation

Nov 27, 2019
Verified review.
Verified review.
"Special thanks to our coordinator Alena Soyak for timely and comprehensive consultations, patient attitude
Good day to all. I would like to leave a review about the clinic and express my deep gratitude to the doctors of this Clinic for their attentive attitude, kindness and a very competent approach. We were warmly welcomed, consulted and hospitalized. During our stay in the clinic, we had everything we needed, the medical staff was responsive. Many thanks to Dr. Stefansky, a very competent doctor. Special thanks to our coordinator Alena Soyak for timely and comprehensive consultations, patient attitude.
About Bookimed service
Definitely satisfied.
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Location

Weizmann St 6, Tel Aviv-Yafo, Israel

FAQ

Targeted therapy: what is it and how does it work?

Targeted therapy (targeted therapy, molecular targeted therapy, molecular targeted therapy) is a medical treatment of cancer using drugs that act specifically on cancer cells and do not harm healthy tissues.

Doctors may prescribe it as the main method of treatment or in combination with other procedures - surgery, radiation and chemotherapy.

How targeted therapy works in oncology

The principle of operation of a targeted drug depends on its type. The American Cancer Society identifies the following goals for targeted therapy:

  • block chemical signals that stimulate the growth and division of cancer cells;
  • change the proteins of cancer cells in such a way that the cells die;
  • prevent the appearance of new blood vessels that feed the tumor;
  • activate the immune system so that it recognizes and destroys tumors on its own;
  • deliver substances to cancer cells that will destroy them.
What are the types of targeted therapy?

Depending on the active substance that is part of the drug, the Canedey Cancer Society distinguishes the following types of molecular targeted therapy:

Monoclonal antibodies

When entering the body, monoclonal antibodies find cancer cells, attach to the shell and trigger a self-destruction mechanism in them.

Monoclonal antibodies also increase the effectiveness of chemotherapy and radiation therapy - they help chemotherapy drugs and radiation to penetrate into the cancer cell and destroy it.

The names of all drugs containing monoclonal antibodies end in “mab” (for example, Pembrolizumab, Trastuzumab, Rituximab, etc.).

Interesting to know:

Monoclonal antibodies are also used in immunotherapy, because they activate the immune system and it begins to destroy the tumor on its own.

Tyrosine kinase inhibitors

Tyrosine kinase inhibitors block the signaling of a cancer cell that causes it to grow.

The name of such drugs ends with “nib” (Imatinib, Gefitinib, etc.)

Apoptosis-inducing drugs

Such drugs activate signals in cancer cells that cause them to die.

Apoptosis-inducing drugs include Oblimersen, Bortezomib, Olaparib.

Angiogenesis inhibitors

They prevent the development of new blood vessels that feed the tumor.

Angiogenesis inhibitors include Sunitinib, Bevacizumab, and Thalidomide.

mTOR inhibitors

The substance blocks a protein that is responsible for the growth and division of cancer cells.

Medications based on mTOR inhibitors - Everolimus, Temsirolimus.

Hormonal medications

Hormone therapy is a subspecies of targeted therapy. It prevents hormones (estrogen, testosterone, and progesterone) from binding to receptors that help cancer cells grow. Due to this, the tumor dies.

How can the treatment take place and how long does it take?

Selection of the drug

To select a targeted therapy drug and determine the duration of treatment, the doctor prescribes an immunohistochemical study - an analysis of tumor tissue obtained by biopsy. It allows you to determine the type of cancer cells and identify genetic mutations and proteins that are targets for targeted drugs.

If the patient has already taken the material, it is necessary to bring blocks and glasses with you to the clinic. Doctors will review them and the procedure will not have to be repeated.

A unique test to select the most effective drug

The FoundationOne tumor test is available at the Ichilov and Assuta Clinic (Israel) and the Anadolu Medical Center (Turkey). It allows you to determine which target drug the tumor is most sensitive to. This test requires special laboratory equipment and doctor's qualifications, therefore it is available only in some clinics around the world.

Taking medication

Targeted therapy is inpatient or outpatient, depending on the general condition of the patient and the need for additional treatment. At the same time, it is not necessary to stay in the country in which you were selected and prescribed the drug. You can buy medicine, return home and take it according to the prescribed regimen in your place of residence.

Duration of treatment

The duration of 1 course of targeted therapy is individual. On average, it is 2 weeks. The doctor determines the number of courses individually for each patient. This is influenced by the diagnosis, general health, disease and body response to drugs.

Can there be side effects?

Because targeted drugs target cancer cells, this treatment is easier than chemotherapy. However, there is a risk of certain complications. The American Cancer Society lists them as:

  • rash;
  • capillary damage;
  • dryness, redness, itching of the skin and eyes;
  • increased sensitivity of the skin to sunlight and slow regeneration;
  • thinning hair and slowing down their growth;
  • high blood pressure;
  • coagulation disorders;
  • puffiness;
  • disorders of the digestive system, thyroid gland, liver, kidneys;
  • fatigue;
  • headache;
  • shortness of breath and other breathing problems;
  • cough.
How is the price of targeted therapy in oncology formed?

The price of targeted therapy depends on:

  • the prescribed drug and its dosage;
  • duration of treatment (number of courses);
  • selected country and clinic.

In our catalog, in the cards of clinics, the price is indicated for 1 course of treatment with targeted drugs. The required number of courses is determined by the attending physician based on the diagnostic results. Therefore, you can find out the final cost of targeted therapy after the doctor gets acquainted with the diagnosis and the results of the examination.

How to arrange treatment?

Leave a request on our website, and a Bookimed coordinating doctor will contact you at a convenient time for you. He will talk about the features of the technique, orient on the cost. Together with the coordinating doctor, you will select the best medical center for your case.

Our care department will help you arrange your travel for treatment and will stay in touch with you from the moment you contact us and even after you return home.

You do not pay for Bookimed services.